Evidence map›Paper›PMID 33954153›Full record

ArticleJournal of hepatocellular carcinoma2021

Impact of Sarcopenia on Two-Year Mortality in Patients with HCV-Associated Hepatocellular Carcinoma After Radiofrequency Ablation.

Ahmed Salman, Mohamed Salman, Ahmed Moustafa, Hossam El-Din Shaaban, Ahmed El-Mikkawy, Safa Labib, Ahmed Youssef, Mahmoud Gouda Omar, Mohamed Matter, Hesham Elkassar

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of hepatocellular carcinoma, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 3 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 3 syntheses or guidelines pooled it, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Ahmed SalmanInternal Medicine Department, Faculty of Medicine, Cairo University, Cairo, Egypt.ORCID 0000-0003-0026-0841
Mohamed SalmanGeneral Surgery Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
Ahmed MoustafaDepartment of Endemic Medicine and Hepatology, Faculty of Medicine, Cairo University, Cairo, Egypt.ORCID 0000-0002-1687-7048
Hossam El-Din ShaabanGastroenterology Department, National Hepatology and Tropical Medicine Research Institute, Cairo, Egypt.ORCID 0000-0002-0832-5382
Ahmed El-MikkawyHepatology and Gastroenterology Department, Theodor Bilharz Research Institute, Cairo, Egypt.
Safa LabibInternal Medicine Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
Ahmed YoussefInternal Medicine Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
Mahmoud Gouda OmarInternal Medicine Department, Faculty of Medicine, Cairo University, Cairo, Egypt.ORCID 0000-0001-9743-4398
Mohamed MatterRadiodiagnosis Department, Faculty of Medicine, Alazhar University, Cairo, Egypt.
Hesham ElkassarInternal Medicine Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
Cairo University · EGAl-Azhar University · EGNational Water Research Center · EGTheodor Bilharz Research Institute · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeRadiofrequency ablation (RFA) appears effective for the treatment of hepatocellular carcinoma (HCC). Evaluation of prognostic factors is imperative for patient selection and improving treatment efficacy. This study aimed to assess sarcopenia as a predictor of the outcome of RFA in patients with HCC.

methodsThis prospective study included all patients with HCC on top of HCV-related cirrhosis who underwent RFA and followed up for a minimum of two years. CT scan was used to determine the skeletal muscle index at the psoas, erector spinae, quadratus lumborum, transversus abdominis, external and internal obliques, and rectus abdominis muscles. Cross-sectional areas were calculated to obtain a lumbar skeletal muscle index (L3-SMI).

resultsA total of 97 patients were enrolled in the study. The L3-SMI was 46.2±12.1 cm

conclusionSarcopenia is a surrogate predictor of overall survival at two years in HCC patients after RFA. Sarcopenia assessment might be an additional prognostic indicator with conventional biomarkers to optimize the selection criteria for receiving RFA for early-stage HCC.

Indexed as

hepatocellular carcinomamortalityradiofrequency ablationsarcopenia

Identifiers

PMID33954153
PMCPMC8092617
OpenAlexW3157297540

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.