Evidence map›Paper›PMID 33953989›Full record

ArticleCase reports in dentistry2021

Occurrence of Recurrent Aphthous Stomatitis (RAS) as a Rare Oral Manifestation in a Patient with Gilbert's Syndrome.

Artak Heboyan, Anna Avetisyan, Hans Erling Skallevold, Dinesh Rokaya, Vinay Marla, Anna Vardanyan

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in dentistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Clinical relevance of the use of DentoxolWorld journal of clinical oncology · 2022
    Trial
  3. Lessons Learned from Liver-on-Chip Platform.Annals of biomedical engineering · 2025
    Review
  4. Review
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Artak HeboyanDepartment of Prosthodontics, Faculty of Stomatology, Yerevan State Medical University, Str. Koryun 2, Yerevan 0025, Armenia.ORCID https://orcid.org/0000-0001-8329-3205
Anna AvetisyanDepartment of Therapeutic Dentistry, Faculty of Stomatology, Yerevan State Medical University, Str. Koryun 2, Yerevan 0025, Armenia.
Hans Erling SkallevoldChristiania Tannlegesenter, Grønland 4, 0188 Oslo, Norway.ORCID https://orcid.org/0000-0002-9083-5188
Dinesh RokayaDepartment of Clinical Dentistry, Walailak University International College of Dentistry, Bangkok 10400, Thailand.ORCID https://orcid.org/0000-0002-3854-667X
Vinay MarlaDepartment of Oral Pathology, Penang International Dental College, Penang 12000, Malaysia.ORCID https://orcid.org/0000-0001-6673-9236
Anna VardanyanDepartment of Prosthodontics, Faculty of Stomatology, Yerevan State Medical University, Str. Koryun 2, Yerevan 0025, Armenia.
Yerevan State Medical University · AMRCSI & UCD Malaysia Campus · MYWalailak University · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recurrent aphthous stomatitis is an ulcerative disease of the oral cavity and can occur in isolation or as a manifestation of many systemic diseases. It is a quite common entity and may hence often be overlooked as an isolated lesion. Gilbert's syndrome is a genetic disorder where a deficiency of an enzyme associated with the conjugation of bilirubin results in unconjugated hyperbilirubinemia. The disease is generally asymptomatic and is aggravated by certain trigger factors. No associated oral manifestations are known. In this case report, we discuss the concomitant presence of recurrent aphthous stomatitis in a patient of Gilbert's syndrome. The presence of such recurrent stomatitis may represent as an oral manifestation of Gilbert's syndrome. Early identification of these entities may improve the overall quality of life of the patient.

Identifiers

PMID33953989
PMCPMC8068538
OpenAlexW3152739345

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.