Evidence map›Paper›PMID 33953973›Full record

ReviewCardiology research and practice2021

Drug-Coated Balloon versus Drug-Eluting Stent in Patients with Small-Vessel Coronary Artery Disease: A Meta-Analysis of Randomized Controlled Trials.

Xinying Wu, Lun Li, Li He

3 registry-linked trialsOpen access · goldAbstract readReview
In one paragraph

Review in Cardiology research and practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 11 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 4 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05292014 completednot on this mapstarted 2022, after this paper: background citation

ANGIOLITE Post-Market Clinical Follow-up Study

TypeobservationalSponsorFundación EPICRan2022 to 2024Enrolled81ConditionsCoronary Artery Disease (CAD), Ischemic Heart DiseaseArmsANGIOLITE
NCT05292092 completednot on this mapstarted 2022, after this paper: background citation

Essential Pro Post-Market Clinical Follow-up Study

TypeobservationalSponsorFundación EPICRan2022 to 2026Enrolled161ConditionsCoronary Artery Disease (CAD), Ischemic Heart DiseaseArmsEssential pro
NCT06631157 recruitingnot on this mapstarted 2025, after this paper: background citation

Essential Pro Post-Market Clinical Follow-up Study

TypeobservationalSponsorFundación EPICRan2025 to 2026Enrolled100ConditionsCoronary Artery Disease, Ischemic Heart DiseaseArmsEssential pro
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 4 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Pooled it
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  5. Observational
  6. Article
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  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Xinying WuDepartment of Cardiology, Wuhan Fourth Hospital, Puai Hospital, Tongji Medical College, Huazhong University of Science and Technology, Han Zheng Street 473, Wuhan 430033, China.ORCID https://orcid.org/0000-0003-3808-5559
Lun LiDepartment of Cardiology, Wuhan Fourth Hospital, Puai Hospital, Tongji Medical College, Huazhong University of Science and Technology, Han Zheng Street 473, Wuhan 430033, China.
Li HeDepartment of Cardiology, Wuhan Fourth Hospital, Puai Hospital, Tongji Medical College, Huazhong University of Science and Technology, Han Zheng Street 473, Wuhan 430033, China.
Wuhan Puai Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPercutaneous coronary intervention (PCI) with drug-eluting stents (DES) of small-vessel coronary artery disease (SVD) is related to an increased risk of in-stent restenosis (ISR) and stent thrombosis (ST). The application of the drug-coated balloon (DCB) for patients with SVD remains controversial.

objectivesAssess the outcomes of DCB in the treatment of SVD compared with DES in patients with SVD.

methodsA meta-analysis of randomized controlled trials (RCTs) published up to June 2020, reporting the outcomes of DCB versus DES in the treatment of SVD, was performed.

resultsFour RCTs with 1227 patients were included. The results indicated that DCB was associated with the decreased risk for myocardial infarction (MI) compared with the DES, but the difference showed no significance (OR 0.50, 95% CI 0.24-1.03,

conclusionCompared with DES, DCB was associated with a decreased risk of MI among patients with SVD, but the difference showed no significance. The application of DCB in SVD is associated with comparable outcomes of death, TVR, and MACE when compared with DES.

Identifiers

PMID33953973
PMCPMC8057900
OpenAlexW3155510843

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.