Evidence map›Paper›PMID 33953916›Full record

ArticleTherapeutic advances in infectious disease

Implementation of a comprehensive intervention focused on hospitalized patients with HIV by an existing stewardship program: successes and lessons learned.

Danya Roshdy, Maggie McCarter, Jacqueline Meredith, Rupal Jaffa, Katie Hammer, Barbara Santevecchi, Nigel Rozario, Jamie Campbell, Michael Leonard, Christopher Polk

Abstract read
In one paragraph

Article in Therapeutic advances in infectious disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Danya RoshdyDepartment of Pharmacy, Carolinas Medical Center, 1000 Blythe Blvd, Charlotte, NC 28203, USA.ORCID https://orcid.org/0000-0003-1223-8983
Maggie McCarterCenter for Outcomes Research and Evaluation, Atrium Health, Charlotte, NC, USA.
Jacqueline MeredithDepartment of Pharmacy, Atrium Health, Charlotte, NC, USA.
Rupal JaffaDepartment of Pharmacy, Atrium Health, Charlotte, NC, USA.
Katie HammerDepartment of Pharmacy, Atrium Health, Charlotte, NC, USA.
Barbara SantevecchiDepartment of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Gainesville, FL, USA.
Nigel RozarioCenter for Outcomes Research and Evaluation, Atrium Health, Charlotte, NC, USA.
Jamie CampbellDepartment of Internal Medicine, Atrium Health, Charlotte, NC, USA.
Michael LeonardDepartment of Internal Medicine, Atrium Health, Charlotte, NC, USA.
Christopher PolkDepartment of Internal Medicine, Atrium Health, Charlotte, NC, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSeveral national organizations have advocated for inpatient antiretroviral stewardship to prevent the consequences of medication-related errors. This study aimed to evaluate the impact of a stewardship initiative on outcomes in people with HIV (PWH).

methodsA pharmacist-led audit and review of adult patients admitted with an ICD-10 code for HIV was implemented to an existing antimicrobial stewardship program. A quasi-experimental, retrospective cohort study was conducted comparing PWH admitted during pre- and post-intervention periods. Rates of antiretroviral therapy (ART)-related errors and infectious diseases (ID) consultation with linkage to care were evaluated through selection of a random sample of patients receiving ART in each period. Length of stay (LOS) and mortality were assessed by analyzing all admissions in the post-intervention period. Clinical outcomes including LOS, 30-day all-cause hospital readmission, and in-hospital and 30-day mortality in the post-intervention group were stratified by patients not on ART, on ART at admission, and started on ART as a result of the intervention.

resultsA total of 100 patients in the pre-intervention period and 103 patients in the post-intervention period were included to assess ART-related errors and linkage to care. A reduction in errors (70.0

conclusionsThis interdisciplinary intervention was successful in reducing inpatient ART-related errors and increasing ID consultation with linkage to care among PWH.

Indexed as

antiretroviral stewardshipHIVmedication-related errorstransitions of care

Identifiers

PMID33953916
PMCPMC8058799

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.