Evidence map›Paper›PMID 33953836›Full record

ArticleOxidative medicine and cellular longevity2021

Epicardial Adipose Tissue Volume Is Associated with High Risk Plaque Profiles in Suspect CAD Patients.

Dongkai Shan, Guanhua Dou, Junjie Yang, Xi Wang, Jingjing Wang, Wei Zhang, Bai He, Yuqi Liu, Yundai Chen, Yang Li

RetractedOpen access · hybridAbstract readRetracted Publication
In one paragraph

Article in Oxidative medicine and cellular longevity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Trial
  2. NSTEMI Risk Prediction with the Combination of the Biomarkers Epicardial Adipose Tissue and Soluble Suppression of Tumorigenicity 2.Medical science monitor : international medical journal of experimental and clinical research · 2025
    Observational
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Dongkai ShanDepartment of Cardiovascular Medicine, Sixth Medical Center, Chinese PLA General Hospital, Beijing, China.
Guanhua DouDepartment of Cardiology, Second Medical Center, Chinese PLA General Hospital, Beijing, China.
Junjie YangDepartment of Cardiovascular Medicine, Sixth Medical Center, Chinese PLA General Hospital, Beijing, China.
Xi WangDepartment of Cardiology, First Medical Center, Chinese PLA General Hospital, Beijing, China.
Jingjing WangDepartment of Cardiology, First Medical Center, Chinese PLA General Hospital, Beijing, China.
Wei ZhangDepartment of Cardiology, First Medical Center, Chinese PLA General Hospital, Beijing, China.
Bai HeDepartment of Cardiology, First Medical Center, Chinese PLA General Hospital, Beijing, China.
Yuqi LiuDepartment of Cardiovascular Medicine, Sixth Medical Center, Chinese PLA General Hospital, Beijing, China.
Yundai ChenDepartment of Cardiovascular Medicine, Sixth Medical Center, Chinese PLA General Hospital, Beijing, China.ORCID https://orcid.org/0000-0003-2252-8992
Yang LiDepartment of Cardiovascular Medicine, Sixth Medical Center, Chinese PLA General Hospital, Beijing, China.ORCID https://orcid.org/0000-0001-5706-1830
Chinese PLA General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore the association between EAT volume and plaque precise composition and high risk plaque detected by coronary computed tomography angiography (CCTA).

methods101 patients with suspected coronary artery disease (CAD) underwent CCTA examination from March to July 2019 were enrolled, including 70 cases acute coronary syndrome (ACS) and 31 cases stable angina pectoris (SAP). Based on CCTA image, atherosclerotic plaque precise compositions were analyzed using dedicated quantitative software. High risk plaque was defined as plaque with more than 2 high risk features (spotty calcium, positive remolding, low attenuation plaque, napkin-ring sign) on CCTA image. The association between EAT volume and plaque composition was assessed as well as the different of correlation between ACS and SAP was analyzed. Multivariable logistic regression analysis was used to explore whether EAT volume was independent risk factors of high risk plaque (HRP).

resultsEAT volume in the ACS group was significantly higher than that of the SAP group (143.7 ± 49.8 cm

conclusionsWith the increasing EAT volume, more dangerous plaque composition burdens increase significantly. EAT volume is a risk predictor of HRP independent of convention cardiovascular risk factors and CACS, which supports the potential impact of EAT on progression of coronary atherosclerotic plaque.

Indexed as

Acute Coronary SyndromeAdipose TissueFemaleHumansMaleMiddle AgedPlaque, AtheroscleroticRisk Factors

Identifiers

PMID33953836
PMCPMC8057896
OpenAlexW3152505220

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.