Evidence map›Paper›PMID 33953827›Full record

ArticleECS transactions2020

Polymer-Modified Carbon Fiber Microelectrodes for Neurochemical Detection of Dopamine and Metabolites.

P M Wonnenberg, A G Zestos

Abstract read
In one paragraph

Article in ECS transactions, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

P M WonnenbergDepartment of Chemistry, Center for Behavioral Neuroscience, American University, Washington, District of Columbia 20016, USA.
A G ZestosDepartment of Chemistry, Center for Behavioral Neuroscience, American University, Washington, District of Columbia 20016, USA.

Funding

Multielectrode Arrays for Neurotransmitter Detection with Fast Scan Cyclic VoltammetryR41NS113702 · NINDS · MICROPROBES FOR LIFE SCIENCE, INC. · PI ZESTOS, ALEXANDROS GEORGE · 2019 to 2019
$145k
NINDS NIH HHS R41 NS113702
6 · The paper itself

Abstract

Carbon-fiber microelectrodes (CFMEs) are considered to be the standard electrodes for neurotransmitter detection. Fast-scan cyclic voltammetry (FSCV), an electro analytical method, has the ability to follow neurochemical dynamics in real time using CFMEs. Improvements in neurochemical detection with CFMEs were previously made through the coating of polymers onto the surface of the carbon-fiber. Polymers such as PEI, PEDOT, and Nafion were electrodeposited onto the surface of the electrodes to enhance neurochemical detection. This work demonstrates applications for enhancements in co-detection of similarly structured neurochemicals such as dopamine, DOPAL, 3-methoxytyramine, DOPAC, and other neurotransmitters. Manipulating the charge and surface structure of the carbon electrode allows for the improvement of sensitivity and selectivity of neurotransmitter detection. The analytes are detected and differentiated by the shape and the peak positions of their respective cyclic voltammograms.

Identifiers

PMID33953827
PMCPMC8096166

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.