Evidence map›Paper›PMID 33953794›Full record

Observational studyComputational and mathematical methods in medicine2021

TAP Test Image Dynamic Tracking Study after Thyroid Cancer Surgery and after Radiotherapy and Chemotherapy.

Changliang Wang, Yongxue Gu, Xiaojuan Men, Peng Sun, Meili Chen

RetractedOpen access · hybridAbstract readObservational StudyRetracted Publication
In one paragraph

Observational study in Computational and mathematical methods in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Changliang WangDepartment of Galactophore Surgery, Weifang People's Hospital, Shandong 261041, China.
Yongxue GuDepartment of Galactophore Surgery, Weifang People's Hospital, Shandong 261041, China.
Xiaojuan MenDepartment of Galactophore Surgery, Weifang People's Hospital, Shandong 261041, China.
Peng SunWeifang Medical University, Shandong 261041, China.
Meili ChenWeifang Brain Hospital Emergency Department, Shandong 261041, China.ORCID https://orcid.org/0000-0001-9784-5912
Weifang People's Hospital · CNWeifang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thyroid cancer is a relatively common endocrine gland malignant tumor; if improper treatment, there will be a high risk of recurrence or metastasis, and abnormal sugar chain glycoprotein (TAP) has a close relationship with the development of the disease; therefore, the purpose of this article is to discuss abnormal sugar chain glycoprotein (TAP) as thyroid cancer curative effect evaluation and radiation and chemotherapy after surgery clinical significance. In this paper, 95 patients with thyroid cancer diagnosed in a hospital were selected as the study objects and treated as the observation group. The clinical and follow-up data of the observation group were retrospectively analyzed. Meanwhile, 55 healthy patients were randomly selected as the control group. TAP, squamous cell carcinoma antigen (SCC) level, and carcinoembryonic antigen (CEA) level were detected in peripheral blood of 95 patients with thyroid cancer before and after treatment. The short-term efficacy was evaluated by chest CT examination, and the changes of the three markers before and after treatment and the correlation with the short-term efficacy of the patients were compared. According to the results of testing, the TAP positive expression in patients before radiotherapy can better predict the recent curative effect has certain clinical value; before radiotherapy TAP positive expression rate was significantly higher than that of healthy people, TAP positive expression quantity decreased obviously after radiation treatment, and patients with a recent radiotherapy curative effect is good or bad and negatively correlated with the degree of TAP protein positive expression; TAP high protein in patients with recent poor radiation effects, prompt the factor can be predicted in the near future curative effect of the molecular markers, and can TAP level for clinicians provide certain reference for targeted therapy.

Indexed as

AdultAgedAntigens, NeoplasmBiomarkers, TumorCarcinoembryonic AntigenCase-Control StudiesCombined Modality TherapyComputational BiologyFemaleGlycoproteinsHumansMaleMiddle AgedNeoplasm ProteinsNeoplasm Recurrence, LocalSerpinsAntigens, NeoplasmBiomarkers, TumorCarcinoembryonic AntigenGlycoproteinsNeoplasm ProteinsSerpinssquamous cell carcinoma-related antigen

Identifiers

PMID33953794
PMCPMC8068541
OpenAlexW3156997074

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.