Evidence map›Paper›PMID 33953744›Full record

ArticleJournal of oncology2021

miR-139-5p Regulates the Proliferation of Acute Promyelocytic Leukemia Cells by Targeting MNT.

Yueyue Fu, Limin Li, Jinxiao Hou, Huibo Li, Chengfang Lv, Hongjuan Yu, Xiaoqian Zhang, Mengyuan Xu, Mingwen Zhang, Hongbin Meng and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Cells · 2022
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Yueyue FuDepartment of Hematology, The First Affiliated Hospital, Harbin Medical University, Harbin 150001, Heilongjiang, China.ORCID https://orcid.org/0000-0002-5373-6367
Limin LiDepartment of Hematology, South University of Science and Technology Hospital, Shenzhen, China.ORCID https://orcid.org/0000-0001-8310-8313
Jinxiao HouDepartment of Hematology, The First Affiliated Hospital, Harbin Medical University, Harbin 150001, Heilongjiang, China.ORCID https://orcid.org/0000-0001-6736-1714
Huibo LiDepartment of Hematology, The First Affiliated Hospital, Harbin Medical University, Harbin 150001, Heilongjiang, China.ORCID https://orcid.org/0000-0001-5386-8629
Chengfang LvDepartment of Hematology, South University of Science and Technology Hospital, Shenzhen, China.ORCID https://orcid.org/0000-0001-7484-6170
Hongjuan YuDepartment of Hematology, South University of Science and Technology Hospital, Shenzhen, China.ORCID https://orcid.org/0000-0002-9382-4943
Xiaoqian ZhangDepartment of Hematology, South University of Science and Technology Hospital, Shenzhen, China.ORCID https://orcid.org/0000-0003-3703-4784
Mengyuan XuDepartment of Hematology, South University of Science and Technology Hospital, Shenzhen, China.ORCID https://orcid.org/0000-0002-0484-0256
Mingwen ZhangDepartment of Hematology, The First Affiliated Hospital, Harbin Medical University, Harbin 150001, Heilongjiang, China.ORCID https://orcid.org/0000-0002-9100-9312
Hongbin MengDepartment of Hematology, The First Affiliated Hospital, Harbin Medical University, Harbin 150001, Heilongjiang, China.ORCID https://orcid.org/0000-0002-8357-8603
Jie LiuDepartment of Hematology, The First Affiliated Hospital, Harbin Medical University, Harbin 150001, Heilongjiang, China.ORCID https://orcid.org/0000-0003-1855-8515
Xin LianDepartment of Hematology, The First Affiliated Hospital, Harbin Medical University, Harbin 150001, Heilongjiang, China.ORCID https://orcid.org/0000-0002-0184-370X
Jiawei FengDepartment of Hematology, The First Affiliated Hospital, Harbin Medical University, Harbin 150001, Heilongjiang, China.ORCID https://orcid.org/0000-0002-1984-0646
Jin ZhouDepartment of Hematology, The First Affiliated Hospital, Harbin Medical University, Harbin 150001, Heilongjiang, China.ORCID https://orcid.org/0000-0003-0228-3940

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute promyelocytic leukemia (APL) patients with progressive leukocytosis are more likely to have various complications and poor outcomes. However, the regulatory roles of microRNAs in the leukocytosis of APL have not been clarified. Our study aims to evaluate the effects of miRNAs on leukocytosis during induction therapy of APL patients and explore its potential mechanisms. During induction treatment, patients with white blood cell count higher than 10 × 10

Identifiers

PMID33953744
PMCPMC8064781

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.