Evidence map›Paper›PMID 33953624›Full record

ArticleRisk management and healthcare policy2021

Risk Management on Pre-Exposure Prophylaxis Adherence of Men Who Have Sex with Multiple Men: A Multicenter Prospective Cohort Study.

Jiaxiu Liu, Ruibin Deng, Bing Lin, Hong Pan, Yuwen Gao, Jianghong Dai, Hao Liang, Ailong Huang, Xiaoni Zhong

Abstract read
In one paragraph

Article in Risk management and healthcare policy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pre-exposure Prophylaxis Adherence Among Men Who Have Sex With Men: A Systematic Review and Meta-analysis.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jiaxiu LiuSchool of Public Health and Management, Chongqing Medical University, Chongqing, 400016, People's Republic of China.ORCID 0000-0003-0086-8558
Ruibin DengSchool of Public Health and Management, Chongqing Medical University, Chongqing, 400016, People's Republic of China.
Bing LinSchool of Public Health and Management, Chongqing Medical University, Chongqing, 400016, People's Republic of China.
Hong PanSchool of Public Health and Management, Chongqing Medical University, Chongqing, 400016, People's Republic of China.
Yuwen GaoSchool of Public Health and Management, Chongqing Medical University, Chongqing, 400016, People's Republic of China.
Jianghong DaiDepartment of Epidemiology and Health Statistics, School of Public Health, Xinjiang Medical University, Xinjiang, People's Republic of China.
Hao LiangDepartment of Epidemiology and Medical Statistics, School of Public Health, Guangxi Medical University, Nanning, People's Republic of China.
Ailong HuangKey Laboratory of Molecular Biology on Infectious Diseases, Ministry of Education, Chongqing Medical University, Chongqing, People's Republic of China.
Xiaoni ZhongSchool of Public Health and Management, Chongqing Medical University, Chongqing, 400016, People's Republic of China.ORCID 0000-0002-8035-1841

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMen who have sex with multiple men (MSMM) belong to a high-risk group for HIV infection, and pre-exposure prophylaxis (PrEP) is an effective measure to prevent the infection. However, few studies on PrEP adherence by MSMM in China exist. We aimed to explore the protective motivation-related factors for PrEP adherence in an HIV-negative MSMM population in Western China and to provide a reference for future risk management and effective prevention strategies.

methodsData were collected from a 2-year follow-up cohort study of PrEP in MSM in China. Rogers' protective motivation theory (PMT) was used to study the PrEP adherence of MSMM, and logistic regression was performed to analyze the influencing factors of PrEP adherence.

resultsA total of 496 MSMM were included in the study: 299 (60.28%) of them in the good adherence group and 197 (39.72%) in the poor adherence group. The threat assessment scores of the good and poor adherence groups were 2.15 ± 0.59 and 2.06 ± 0.47, respectively, and the response assessment scores were 2.81 ± 0.62 and 2.74 ±0.62, respectively. Poor PrEP adherence was associated with on-demand PrEP medication (OR=0.670), students at school (OR=1.837), occasional condom use (OR=1.621), and good HIV knowledge (OR= 0.659). The higher the threat assessment score, the higher the susceptibility; and the lower the response cost, the stronger the protection motivation and the less likely MSMM were to have poor adherence.

conclusionOn-demand PrEP medication is more conducive to adherence. Preventive management should focus on MSMMs who are students at school, those who occasionally use condoms, and those with poor HIV knowledge. Improving threat perception and susceptibility, and controlling and reducing the response cost can effectively improve PrEP adherence, and the subsequent application of PMT during intervention research can provide a reference for HIV prevention in MSMM.

Indexed as

adherenceMSMmultiple sexual partnersPrEPprotective motivation theoryWestern China

Identifiers

PMID33953624
PMCPMC8092636

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.