Evidence map›Paper›PMID 33953592›Full record

ArticleClinical and experimental gastroenterology2021

Gastroparesis Symptoms Associated with Intestinal Hypomotility: An Explorative Study Using Wireless Motility Capsule.

Mattis Bekkelund, Dag A Sangnes, Eirik Søfteland, Lars Aabakken, Martin Biermann, Elisabeth K Steinsvik, Trygve Hausken, Georg Dimcevski, Jan Gunnar Hatlebakk

Open access · goldAbstract read
In one paragraph

Article in Clinical and experimental gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Mattis BekkelundDepartment of Clinical Medicine, University of Oslo, Oslo, Norway.ORCID 0000-0002-6710-7457
Dag A SangnesNorwegian Competence Centre for Functional Gastrointestinal Disorders, Department of Medicine, Haukeland University Hospital, Bergen, Norway.ORCID 0000-0002-9601-1593
Eirik SøftelandDepartment of Medicine, Haukeland University Hospital, Bergen, Norway.ORCID 0000-0002-7221-1013
Lars AabakkenDepartment of Clinical Medicine, University of Oslo, Oslo, Norway.
Martin BiermannDepartment of Clinical Medicine, University of Bergen, Bergen, Norway.ORCID 0000-0002-5550-1035
Elisabeth K SteinsvikNorwegian Competence Centre for Functional Gastrointestinal Disorders, Department of Medicine, Haukeland University Hospital, Bergen, Norway.
Trygve HauskenNorwegian Competence Centre for Functional Gastrointestinal Disorders, Department of Medicine, Haukeland University Hospital, Bergen, Norway.
Georg DimcevskiDepartment of Clinical Medicine, University of Bergen, Bergen, Norway.
Jan Gunnar HatlebakkNorwegian Competence Centre for Functional Gastrointestinal Disorders, Department of Medicine, Haukeland University Hospital, Bergen, Norway.ORCID 0000-0001-9710-7733
Haukeland University Hospital · NOOslo University Hospital · NOUniversity of Oslo · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveGastric emptying measurements are mandatory in gastroparesis diagnostics, but the association between delayed emptying and symptoms is questionable. It is imperative to find biomarkers better correlated to symptom generation. Hence, we examined the association between symptom severity and gastrointestinal motility measured by wireless motility capsule. PATIENTS AND

methodsIn this prospective single-centre study, patients with gastroparesis symptoms were simultaneously investigated with gastric emptying scintigraphy and wireless motility capsule, measuring regional transit times and contractility parameters. Symptom severity was assessed with the Patient Assessment of Upper Gastrointestinal Symptom Severity Index (PAGI-SYM), including the Gastroparesis Cardinal Symptom Index (GCSI).

resultsWe included 107 patients (70% women). In the whole patient group, nausea correlated with the gastric (

conclusionIn patients with gastroparesis symptoms, we found that symptom severity was associated with intestinal hypomotility. Based on these results, gastroparesis diagnostics should also include an evaluation of the small bowel and colon.

Indexed as

gastric emptyinggastrointestinal motilitygastroparesisgastroparesis-like syndromescintigraphysmall bowelwireless motility capsule

Identifiers

PMID33953592
PMCPMC8088984
OpenAlexW3157287402

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.