ArticleJournal of medical physics
Is Synchronous Bilateral Breast Irradiation Using Flattening Filter-Free Beam-Based Volumetric-Modulated Arc Therapy Beneficial? A Dosimetric Study.
Article in Journal of medical physics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed, 0 citations in OpenAlex.
- Hypofractionated and conventionally fractionated radiotherapy for synchronous bilateral breast cancer: clinical and dosimetric outcomes.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2026Article
- Dosimetric comparison of three different radiotherapy regimens for bilateral breast cancer.Biomedical engineering online · 2026Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
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Abstract
objectiveThe aim of this study is to validate the clinical use of flattening filter-free (FFF) beam-based volumetric-modulated arc therapy (VMAT) in synchronous bilateral breast carcinoma (SBBC) patient treatments and to compare with flattening filtered (FF) beam-based VMAT. MATERIALS AND
methodsComputed tomography images of 15 SBBC patients were taken for this study. A dose of 50 Gy in 25 fractions was prescribed to planning target volume (PTV). VMAT plans were generated using both FFF and FF 6 MV X-ray beams in Eclipse treatment planning system. PTV and organs at risk (OARs) doses were analyzed quantitatively using dose-volume histograms (DVHs) to meet plan objectives. Pretreatment point and planar dosimetry were performed.
resultsThe findings were reported as mean ± 1 standard deviation. PTV volume receiving 95% of the prescribed dose was 95.71% ± 0.65% for FF-VMAT and 95.45% ± 1.33% for FFF-VMAT (
conclusionThe planning objective parameters achieved using FFF-based VMAT showed that FFF can also be used clinically to treat bilateral breast carcinomas and the low-dose lung volumes were still lesser with FFF-VMAT plans than FF-VMAT.
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