ArticleBulletin of the World Health Organization2021
Eliminating mother-to-child transmission of human immunodeficiency virus, syphilis and hepatitis B in sub-Saharan Africa.
Article in Bulletin of the World Health Organization, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.
- A systematic review on health systems integrated approach towards elimination of HIV, syphilis and viral hepatitis as public health threats in sub-Saharan Africa.The Pan African medical journal · 2026Pooled it
- Integrating point-of-care screening for curable sexually transmitted infections with HIV, syphilis and hepatitis B screening in antenatal care services in Zimbabwe: a mixed-methods process evaluation.BMJ global health · 2025Trial
- The Level of Knowledge, Attitude, Practice, and Adherence of Obstetricians and Gynecologists Towards the Triple Elimination Program (HIV, Syphilis, Hepatitis B) in Maternal Services at Government and Private Hospitals in Jakarta.International journal of environmental research and public health · 2026Article
- High screening coverage and positivity rates of HIV, syphilis, and hepatitis B among pregnant women accessing antenatal care in Sierra Leone.Public health action · 2026Article
- Distribution of Mother-to-Child Transmitted (MTCT) Infections and Socioeconomic Vulnerability Within the Gran Chaco Region.Tropical medicine and infectious disease · 2026Article
- Integrated Service Delivery Models for Triple Elimination of Mother to Child Transmission of Human Immunodeficiency Virus, Syphilis, and Hepatitis B Virus: A Global Systematic Review and Meta-Analysis.Healthcare (Basel, Switzerland) · 2026Review
- Progress towards the elimination of vertical transmission of HIV, syphilis and hepatitis B in 21 high-burden countries.Journal of the International AIDS Society · 2026Review
- Sociodemographic and obstetric determinants of HIV infection among pregnant women in Cameroon: a contribution toward the elimination of vertical transmission in low- and middle-income countries.BMC infectious diseases · 2026Article
- Optimizing hepatitis B diagnosis for mothers in a low-resource setting: A field pilot of Xpert point-of-care viral load testing in Ugandan antenatal clinics.PLOS global public health · 2026Article
- Assessing progress towards the elimination of mother-to-child transmission of syphilis in Peru: A national retrospective analysis.PLOS global public health · 2026Article
- Facilitators, barriers and service availability for delivering integrated care for the triple elimination of HIV, syphilis and hepatitis B vertical transmission in Uganda: a multi-site explanatory mixed methods study.BMC health services research · 2025Article
- Sexually transmitted infections and migration in Uganda: a population-based study.Sexually transmitted infections · 2025Article
- The contribution of PrEP programmes to triple elimination efforts: a cross-sectional study of status and opportunities.Frontiers in reproductive health · 2025Article
- Comparative evaluation of the antibacterial effect of ultraviolet radiation on alginate and condensation silicone impressions compared to hypochlorite.Dental research journal · 2025Article
- Hepatitis B seroprevalence among HIV-positive adults in the Free State, South Africa.Southern African journal of HIV medicine · 2025Article
- Care of Pregnant Women Living with Human Immunodeficiency Virus.Clinics in perinatology · 2024Review
- Prevalence of sexually transmitted infection in pregnancy and their association with adverse birth outcomes: a case-control study at Queen Elizabeth Central Hospital, Blantyre, Malawi.Sexually transmitted infections · 2024Article
- Patient perspective on the elimination mother-to-child transmission of HIV, syphilis, and hepatitis B in Bali, Indonesia: a qualitative study.BMC public health · 2024Article
- Proportion of pregnant women with HBV infection eligible for antiviral prophylaxis to prevent vertical transmission: A systematic review and meta-analysis.JHEP reports : innovation in hepatology · 2024Article
- Factors influencing the implementation of integrated screening for HIV, syphilis, and hepatitis B for pregnant women in Nepal: A qualitative study.PLOS global public health · 2024Article
Corrections and comments
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Authors and funding
22 authors at 6 institutions in 5 countries.
Funding
Abstract
Triple elimination is an initiative supporting the elimination of mother-to-child transmission of three diseases - human immunodeficiency virus (HIV) infection, syphilis and hepatitis B. Significant progress towards triple elimination has been made in some regions, but progress has been slow in sub-Saharan Africa, the region with the highest burden of these diseases. The shared features of the three diseases, including their epidemiology, disease interactions and core interventions for tackling them, enable an integrated health-systems approach for elimination of mother-to-child transmission. Current barriers to triple elimination in sub-Saharan Africa include a lack of policies, strategies and resources to support the uptake of well established preventive and treatment interventions. While much can be achieved with existing tools, the development of new products and models of care, as well as a prioritized research agenda, are needed to accelerate progress on triple elimination in sub-Saharan Africa. In this paper we aim to show that health systems working together with communities in sub-Saharan Africa could deliver rapid and sustainable results towards the elimination of mother-to-child transmission of all three diseases. However, stronger political support, expansion of evidence-based interventions and better use of funding streams are needed to improve efficiency and build on the successes in prevention of mother-to-child transmission of HIV. Triple elimination is a strategic opportunity to reduce the morbidity and mortality from HIV infection, syphilis and hepatitis B for mothers and their infants within the context of universal health coverage.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.