Evidence map›Paper›PMID 33953322›Full record

ReviewExperimental & molecular medicine2021

Severe fever with thrombocytopenia syndrome virus: emerging novel phlebovirus and their control strategy.

Mark Anthony Casel, Su Jin Park, Young Ki Choi

Open access · goldAbstract readReview
In one paragraph

Review in Experimental & molecular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 186 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
186citing papers in PubMed, 4 pooled it
11.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

186 citing papers in PubMed, 4 syntheses or guidelines pooled it, 257 citations in OpenAlex.

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  19. SFTSV NSs protein is a tick antiviral RNAi response suppressor.Proceedings of the National Academy of Sciences of the United States of America · 2026
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126 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Mark Anthony CaselCollege of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Republic of Korea.
Su Jin ParkResearch Institute of Life Science, Gyeongsang National University, Jinju, Republic of Korea.
Young Ki ChoiCollege of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Republic of Korea. choiki55@chungbuk.ac.kr.ORCID http://orcid.org/0000-0002-0872-0147
Chungbuk National University · KRGyeongsang National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An emerging infectious disease first identified in central China in 2009, severe fever with thrombocytopenia syndrome (SFTS) was found to be caused by a novel phlebovirus. Since SFTSV was first identified, epidemics have occurred in several East Asian countries. With the escalating incidence of SFTS and the rapid, worldwide spread of SFTSV vector, it is clear this virus has pandemic potential and presents an impending global public health threat. In this review, we concisely summarize the latest findings regarding SFTSV, including vector and virus transmission, genotype diversity and epidemiology, probable pathogenic mechanism, and clinical presentation of human SFTS. Ticks most likely transmit SFTSV to animals including humans; however, human-to-human transmission has been reported. The majority of arbovirus transmission cycle includes vertebrate hosts, and potential reservoirs include a variety of both domestic and wild animals. Reports of the seroprevalence of SFTSV in both wild and domestic animals raises the probability that domestic animals act as amplifying hosts for the virus. Major clinical manifestation of human SFTS infection is high fever, thrombocytopenia, leukocytopenia, gastrointestinal symptoms, and a high case-fatality rate. Several animal models were developed to further understand the pathogenesis of the virus and aid in the discovery of therapeutics and preventive measures.

Indexed as

Disease SusceptibilityAnimalsCommunicable Disease ControlCommunicable Diseases, EmergingDisease ManagementDisease Models, AnimalGenetic VariationHost-Pathogen InteractionsHumansPhlebovirusReassortant VirusesSeroepidemiologic StudiesSevere Fever with Thrombocytopenia SyndromeSymptom AssessmentViral Zoonoses

Identifiers

PMID33953322
PMCPMC8178303
OpenAlexW3157853377

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.