Evidence map›Paper›PMID 33953252›Full record

ArticleScientific reports2021

A numerical investigation of changes in lens shape during accommodation.

I Cabeza-Gil, J Grasa, B Calvo

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. A Brillouin microscopy analysis of the crystalline lenses of Chinese adults with myopia.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
    Article
  4. Article
  5. On the Cranial Nerves.NeuroSci · 2024
    Review
  6. Article
  7. Investigation of crystalline lens overshooting:Frontiers in bioengineering and biotechnology · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

I Cabeza-GilAragón Institute of Engineering Research (i3A), University of Zaragoza, Mariano Esquillor s/n, Zaragoza, 50018, Spain. iulen@unizar.es.
J GrasaAragón Institute of Engineering Research (i3A), University of Zaragoza, Mariano Esquillor s/n, Zaragoza, 50018, Spain.
B CalvoAragón Institute of Engineering Research (i3A), University of Zaragoza, Mariano Esquillor s/n, Zaragoza, 50018, Spain.
Universidad de Zaragoza · ESBiomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this study was to investigate how the mechanical properties and geometry of the lens influence the changes in lens shape during accommodation. To do so, ex vivo stretching tests of the isolated lens were simulated via finite element analysis. In these tests, the lens is stretched from the accommodated state to the non-accommodated state. Several key characteristics of the lens were studied: the stiffness gradient of the lens material, the distribution of the capsule thickness, the mechanical properties of the capsule and the material comprising the lens, nucleus and cortex, and the influence of two different age-related lens geometries (17 and 29 y/o subjects). To determine the effects on the changes in lens shape during accommodation, changes in the anterior and posterior radius, the lens and nucleus thicknesses and the equatorial lens diameter were analysed. The results suggest that multiple factors exert statistically significant influences on how the lens changes its shape, but two factors predominate over the rest: the stiffness ratio between the nucleus and cortex and the stiffness of the capsule, specifically the posterior surface.

Indexed as

Accommodation, OcularAdolescentAdultBiomechanical PhenomenaElasticityFinite Element AnalysisHumansLens, CrystallineModels, Biological

Identifiers

PMID33953252
PMCPMC8100116
OpenAlexW3157331850

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.