Evidence map›Paper›PMID 33952781›Full record

ArticleThe Journal of veterinary medical science2021

A systematic study of Tupaia as a model for human acute hepatitis B infection.

Jun Li, Tong-Dong Shi, Jun-Feng Han, Xing-Guang Zeng, Cui-Li Fan, Chao Han, Hong-Li Liu, Yu-Zhang Wu

Open access · diamondAbstract read
In one paragraph

Article in The Journal of veterinary medical science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Jun LiInstitute of Immunology, Third Military Medical University, No. 30 Gaotanyan Street, Shapingba District, Chongqing 400038, China.
Tong-Dong ShiDivision of Infectious Diseases, The Second Affiliated of Chongqing University of Medical Science, No. 74 Linjiang Rd, Yuzhong District, Chongqing 400038, China.
Jun-Feng HanInstitute of Immunology, Third Military Medical University, No. 30 Gaotanyan Street, Shapingba District, Chongqing 400038, China.
Xing-Guang ZengPharm Star Biotechnology Co., Ltd., No. 99 Hongcaofang Street, Chongqing 400038, China.
Cui-Li FanHEP Biotechnology Co., Ltd., No. 720 Cailun Rd, Shanghai 201203, China.
Chao HanInstitute of Immunology, Third Military Medical University, No. 30 Gaotanyan Street, Shapingba District, Chongqing 400038, China.
Hong-Li LiuHEP Biotechnology Co., Ltd., No. 720 Cailun Rd, Shanghai 201203, China.
Yu-Zhang WuInstitute of Immunology, Third Military Medical University, No. 30 Gaotanyan Street, Shapingba District, Chongqing 400038, China.
Army Medical University · CNShanghai CASB Biotechnology (China) · CNChongqing Medical and Pharmaceutical College · CNDalian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The molecular features of hepatitis B virus (HBV) infection, eradication, and pathogenesis are poorly understood, partly due to the lack of an adequate animal model that faithfully reproduces the course of infection. Although Tupaia belangeri were previously recognized as HBV-susceptible animals, the course of infection in adult tupaias remains obscure. Herein, we performed a longitudinal study and demonstrated that adult tupaias were efficiently infected (90% infection rate) with 10

Indexed as

Hepatitis BTupaiaAnimalsDNA, CircularDNA, ViralHepatitis B Surface AntigensHumansLiverLongitudinal StudiesDNA, CircularDNA, ViralHepatitis B Surface Antigensacute infectionhepatitis B viruspathogenesissmall animal modelviral replication

Identifiers

PMID33952781
PMCPMC8267197
OpenAlexW3159445062

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.