Evidence map›Paper›PMID 33952721›Full record

ArticleAging2021

Bioinformatic analyses and experimental validation of the role of m6A RNA methylation regulators in progression and prognosis of adrenocortical carcinoma.

Fangshi Xu, Yibing Guan, Yubo Ma, Li Xue, Peng Zhang, Xiaojie Yang, Tie Chong

Open access · greenAbstract readValidation Study
In one paragraph

Article in Aging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 37 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Fangshi XuDepartment of Medicine, Xi'an Jiaotong University, Xi'an, Shaanxi 710061, China.
Yibing GuanDepartment of Medicine, Xi'an Jiaotong University, Xi'an, Shaanxi 710061, China.
Yubo MaDepartment of Medicine, Xi'an Jiaotong University, Xi'an, Shaanxi 710061, China.
Li XueDepartment of Urology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710000, China.
Peng ZhangDepartment of Urology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710000, China.
Xiaojie YangDepartment of Urology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710000, China.
Tie ChongDepartment of Urology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710000, China.
Second Affiliated Hospital of Xi'an Jiaotong University · CNXi'an Jiaotong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

M6A-related genes have been proven to play an important role in many cancers. However, the role of that in adrenocortical carcinoma (ACC) has not been fully elucidated. In the present study, 77 ACC samples from TCGA database were divided into localized (

Indexed as

Epigenesis, GeneticNomogramsAdenosineAdrenal CortexAdrenal Cortex NeoplasmsAdrenalectomyAdrenocortical CarcinomaAgedBiomarkers, TumorCell Line, TumorCell ProliferationComputational BiologyDatasets as TopicDisease ProgressionFemaleGene Expression ProfilingAdenosineBiomarkers, TumorHeterogeneous-Nuclear Ribonucleoprotein Group CHNRNPC protein, humanImmune Checkpoint InhibitorsN-methyladenosineRBM15 protein, humanRNARNA-Binding Proteinsadrenocortical carcinomamethylationN6-methyladenosineprognosisrisk signature

Identifiers

PMID33952721
PMCPMC8109058
OpenAlexW3158934397

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.