Evidence map›Paper›PMID 33952688›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

PIP

Scott Earley, David Kleinfeld

Abstract readComment
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Faulty TRPM4 channels underlie age-dependent cerebral vascular dysfunction in Gould syndrome.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
4 · The record

Corrections and comments

  • Comment on
    PIP2021
5 · Who and what money

Authors and funding

2 authors.

Scott EarleyDepartment of Pharmacology, University of Nevada, Reno, School of Medicine, Reno, NV 89557-0318; searley@med.unr.edu.ORCID 0000-0001-9560-2941
David KleinfeldDepartment of Physics, University of California San Diego, La Jolla, CA 92093.

Funding

Transgenic Animal Genotyping and Phenotyping CoreP20GM130459 · NIGMS · UNIVERSITY OF NEVADA RENO · PI Nathan Grainger · 2019 to 2026
$20.3M
Resilient versus fragile aspects of blood flow in the mammalian brainR35NS097265 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI KLEINFELD, DAVID · 2017 to 2024
$6.8M
TRP channels as fundamental sensors of the cerebral microcirculationR35HL155008 · NHLBI · UNIVERSITY OF ROCHESTER · PI Scott Earley · 2021 to 2026
$5.5M
Resting state connectivity: Biophysical basis for and improved fMRI measurementsR01MH111438 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI KLEINFELD, DAVID, ROSEN, BRUCE R · 2016 to 2020
$5.2M
The Neural Mechanisms of HypertensionR01HL122770 · NHLBI · UNIVERSITY OF ROCHESTER · PI FENG EARLEY, YUMEI · 2015 to 2023
$4.2M
Mechanisms of Functional Vascular Impairment In Genetic Models of Cerebral Small Vessel DiseaseRF1NS110044 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI EARLEY, SCOTT, GOULD, DOUGLAS · 2018 to 2022
$3.3M
Role of ANO1 Channels and Its Regulation by PIP2 in EC-Coupling in Pulmonary Artery MyocytesR01HL146054 · NHLBI · UNIVERSITY OF NEVADA RENO · PI EARLEY, SCOTT, LEBLANC, NORMAND · 2019 to 2022
$2.0M
Development and validation of novel models for cerebral small vessel disease and vascular cognitive impairmentR61NS115132 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHAUMEIL, MYRIAM MARIANNE, EARLEY, SCOTT · 2019 to 2020
$1.1M
NHLBI NIH HHS R01 HL122770NHLBI NIH HHS R01 HL146054NHLBI NIH HHS R35 HL155008NIGMS NIH HHS P20 GM130459NIMH NIH HHS R01 MH111438NINDS NIH HHS R35 NS097265NINDS NIH HHS R61 NS115132NINDS NIH HHS RF1 NS110044
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Neurovascular CouplingCerebrovascular CirculationPhosphatidylinositol 4,5-DiphosphatePhosphatidylinositol 4,5-Diphosphate

Identifiers

PMID33952688
PMCPMC8166173

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.