Evidence map›Paper›PMID 33952660›Full record

ArticlemSphere2021

IL-1R1-Dependent Signals Improve Control of Cytosolic Virulent Mycobacteria

Sanne van der Niet, Maaike van Zon, Karin de Punder, Anita Grootemaat, Sofie Rutten, Simone J C F M Moorlag, Diane Houben, Astrid M van der Sar, Wilbert Bitter, Roland Brosch and 6 more

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 3 countries.

Sanne van der NietElectron Microscopy Centre Amsterdam, Amsterdam University Medical Centre AMC, Amsterdam, The Netherlands.
Maaike van ZonNetherlands Cancer Institute, Amsterdam, The Netherlands.
Karin de PunderNetherlands Cancer Institute, Amsterdam, The Netherlands.
Anita GrootemaatElectron Microscopy Centre Amsterdam, Amsterdam University Medical Centre AMC, Amsterdam, The Netherlands.
Sofie RuttenElectron Microscopy Centre Amsterdam, Amsterdam University Medical Centre AMC, Amsterdam, The Netherlands.
Simone J C F M MoorlagNetherlands Cancer Institute, Amsterdam, The Netherlands.
Diane HoubenNetherlands Cancer Institute, Amsterdam, The Netherlands.
Astrid M van der SarAmsterdam University Medical Centre VUMC, Amsterdam, The Netherlands.
Wilbert BitterAmsterdam University Medical Centre VUMC, Amsterdam, The Netherlands.
Roland BroschUnit for Integrated Mycobacterial Pathogenomics, CNRS UMR 3525, Paris, France.ORCID 0000-0003-2587-3863
Rogelio Hernandez PandoNational Institute of Medical Sciences and Nutrition, Mexico City, Mexico.
Maria T PenaDepartment of Health and Human Services, Health Resources and Services Administration, Healthcare Systems Bureau, National Hansen's Disease Programs, Baton Rouge, Louisiana, USA.
Peter J PetersNetherlands Cancer Institute, Amsterdam, The Netherlands.
Eric A ReitsElectron Microscopy Centre Amsterdam, Amsterdam University Medical Centre AMC, Amsterdam, The Netherlands.
Katrin D Mayer-BarberInflammation and Innate Immunity Unit, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Nicole N van der WelElectron Microscopy Centre Amsterdam, Amsterdam University Medical Centre AMC, Amsterdam, The Netherlands n.n.vanderwel@amsterdamumc.nl.ORCID 0000-0001-6392-3417
The Netherlands Cancer Institute · NLUniversity of Amsterdam · NLAmsterdam University Medical Centers · NLCentre National de la Recherche Scientifique · FRHealth Resources and Services Administration · USNational Institutes of Health · US

Funding

Innate inflammatory responses during pulmonary infectionsZIAAI001207 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI MAYER-BARBER, KATRIN · 2015 to 2025
$13.6M
Role of Tuberculosinyl Metabolites in M. Tuberculosis VirulenceR01AI116604 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI MOODY, DAVID BRANCH · 2015 to 2019
$2.4M
NIAID NIH HHS R01 AI116604
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsArmadillosBacterial TranslocationCytosolFemaleHumansLeprosyMaleMiceMice, Inbred BALB CMice, SCIDMycobacteriumPhagosomesReceptors, Interleukin-1Signal TransductionSkinReceptors, Interleukin-1cytosolic localizationIL-1 receptor 1lysosomelysosomesMycobacterium lepraeMycobacterium marinumMycobacterium tuberculosisphagolysosomal fusionphagosomephagosomes

Identifiers

PMID33952660
PMCPMC8103984
OpenAlexW3159401926

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.