Evidence map›Paper›PMID 33952659›Full record

ArticlemSphere2021

HIV-1 Infection Alters the Viral Composition of Plasma in Men Who Have Sex with Men.

Kai Liu, Yanpeng Li, Rong Xu, Yan Zhang, Chenli Zheng, Zhenzhou Wan, Hao Li, Zhengrong Yang, Xia Jin, Pei Hao and 2 more

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 35 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Kai Liu *Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, China.
Yanpeng Li *Shanghai Clinical Research Center for Infectious Disease (HIV/AIDS), Shanghai Public Health Clinical Center, Fudan University, Shanghai, China.ORCID 0000-0002-0643-4809
Rong XuKey Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, China.
Yan ZhangShenzhen Center for Disease Control and Prevention, Shenzhen, China.
Chenli ZhengShenzhen Center for Disease Control and Prevention, Shenzhen, China.
Zhenzhou WanMedical Laboratory of Taizhou Fourth People's Hospital, Taizhou, China.
Hao LiShenzhen Center for Disease Control and Prevention, Shenzhen, China.
Zhengrong YangShenzhen Center for Disease Control and Prevention, Shenzhen, China.
Xia JinShanghai Clinical Research Center for Infectious Disease (HIV/AIDS), Shanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Pei HaoKey Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, China phao@ips.ac.cn szhaojin@gmail.com zhangcy1999@shphc.org.cn.
Jin ZhaoShenzhen Center for Disease Control and Prevention, Shenzhen, China phao@ips.ac.cn szhaojin@gmail.com zhangcy1999@shphc.org.cn.
Chiyu ZhangShanghai Clinical Research Center for Infectious Disease (HIV/AIDS), Shanghai Public Health Clinical Center, Fudan University, Shanghai, China phao@ips.ac.cn szhaojin@gmail.com zhangcy1999@shphc.org.cn.
Shenzhen Center for Disease Control and Prevention · CNChinese Academy of Sciences · CNShanghai Public Health Clinical Center · CNTaizhou Fourth People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Altered gut virome and expanded abundance of certain viruses were found in HIV-1-infected individuals. It remains largely unknown how plasma virus composition changes during HIV-1 infection and antiretroviral therapy (ART). We performed viral metagenomic analysis on viral particles enriched from human plasma from 101 men who have sex with men (MSM) with or without HIV-1 infection and whether or not on ART and compared the differences in the plasma virome. An increased plasma viral abundance of main eukaryotic viruses was observed during HIV-1 infection in MSM, especially in AIDS patients (CD4

Indexed as

AdultHIV-1HIV InfectionsHomosexuality, MaleHumansMaleMetagenomicsViral LoadViromeYoung Adultanellovirus,HIV-1 infectionMSMpegivirusplasma viromeviral metagenome

Identifiers

PMID33952659
PMCPMC8103983
OpenAlexW3159425752

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.