Evidence map›Paper›PMID 33952571›Full record

ArticleBMJ case reports2021

Reactive non-sexually related acute genital ulcers associated with COVID-19.

Jill M Krapf, Rachel K Casey, Andrew T Goldstein

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
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  11. A case of COVID-19-related acute genital ulceration in a male.International journal of STD & AIDS · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jill M KrapfGynecology, Center for Vulvovaginal Disorders, Washington, DC, USA jillkrapf@gmail.com.ORCID http://orcid.org/0000-0002-8695-0570
Rachel K CaseyPediatric Specialists of Virginia, Inova Fairfax Medical Campus, Department of Obstetrics and Gynecology, Fairfax, Virginia, USA.
Andrew T GoldsteinGynecology, Center for Vulvovaginal Disorders, Washington, DC, USA.ORCID http://orcid.org/0000-0003-3486-2402
George Washington University · USInova Fairfax Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute genital ulcers (AGU), known as Lipschütz ulcers, are painful vulvar ulcers typically affecting non-sexually active girls and women. AGU have been associated with viral infections, namely, Epstein-Barr virus (EBV). Here, we describe a case of AGU in the setting of SARS-CoV-2 in a non-sexually active adolescent girl hospitalised for pain control and urinary retention, who failed a course of oral corticosteroids and then improved with colchicine. Testing for herpes simplex virus, EBV and Behcet's syndrome were all negative. Testing for SARS-CoV-2 was positive. COVID-19 increases cytokines such as tumour necrosis factor alpha, which has been shown to affect endothelial cell adhesion and neutrophil chemotaxis, leading to aphthosis.

Indexed as

COVID-19Epstein-Barr Virus InfectionsAdolescentFemaleGenitaliaHerpesvirus 4, HumanHumansSARS-CoV-2Ulcerdermatologygenital ulcersinfectious diseasesvulvovaginal disorders

Identifiers

PMID33952571
PMCPMC8103359
OpenAlexW3157149449

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.