Evidence map›Paper›PMID 33952561›Full record

ReviewBMJ case reports2021

Massive metoprolol overdose requiring ECMO: brief review of the evidence behind recommended treatments.

Shameen Salam, Brandon Nornhold, Jihad Mallat

Open access · greenAbstract readReviewCase Reports
In one paragraph

Review in BMJ case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Shameen SalamCritical Care Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, UAE shameen.salam.ccf@gmail.com.ORCID http://orcid.org/0000-0003-4748-3700
Brandon NornholdDepartment of Clinical Pharmacology, St Vincent's Hospital and Research Center, Erie, Pennsylvania, USA.
Jihad MallatCritical Care Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, UAE.
Cleveland Clinic · USSt. Vincent's Birmingham · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A man in his late 60s developed shock after ingesting 7500 mg of metoprolol tartrate that was refractory to all medical treatment including hyperinsulinaemic euglycaemia, intravenous lipid emulsion and dialysis, eventually needing rescue extracorporeal membrane oxygenation. A brief review of the recommended treatments in beta-blocker overdose is therefore warranted.

Indexed as

Drug OverdoseExtracorporeal Membrane OxygenationFat Emulsions, IntravenousHumansMaleMetoprololRenal DialysisFat Emulsions, IntravenousMetoprololadult intensive carecardiovascular systemtoxicology

Identifiers

PMID33952561
PMCPMC8103398
OpenAlexW3157657583

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.