Evidence map›Paper›PMID 33952243›Full record

ArticleBMC musculoskeletal disorders2021

Knee pain trajectories over 18 months in non-Hispanic Black and non-Hispanic White adults with or at risk for knee osteoarthritis.

Alisa J Johnson, Terrie Vasilopoulos, Staja Q Booker, Josue Cardoso, Ellen L Terry, Keesha Powell-Roach, Roland Staud, Daniel A Kusko, Adriana S Addison, David T Redden and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC musculoskeletal disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Alisa J Johnson *Pain Research and Intervention Center of Excellence (PRICE), University of Florida, Gainesville, FL, USA. alisa.johnson@ufl.edu.
Terrie Vasilopoulos *Department of Anesthesiology, College of Medicine, University of Florida, Gainesville, FL, USA.
Staja Q BookerPain Research and Intervention Center of Excellence (PRICE), University of Florida, Gainesville, FL, USA.
Josue CardosoPain Research and Intervention Center of Excellence (PRICE), University of Florida, Gainesville, FL, USA.
Ellen L TerryPain Research and Intervention Center of Excellence (PRICE), University of Florida, Gainesville, FL, USA.
Keesha Powell-RoachPain Research and Intervention Center of Excellence (PRICE), University of Florida, Gainesville, FL, USA.
Roland StaudDepartment of Rheumatology, College of Medicine, University of Florida, Gainesville, FL, USA.
Daniel A KuskoDepartment of Psychology, College of Arts and Sciences, University of Alabama at Birmingham, Birmingham, AL, USA.
Adriana S AddisonDepartment of Psychology, College of Arts and Sciences, University of Alabama at Birmingham, Birmingham, AL, USA.
David T ReddenDepartment of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA.
Burel R GoodinDepartment of Psychology, College of Arts and Sciences, University of Alabama at Birmingham, Birmingham, AL, USA.
Roger B FillingimPain Research and Intervention Center of Excellence (PRICE), University of Florida, Gainesville, FL, USA.
Kimberly T SibillePain Research and Intervention Center of Excellence (PRICE), University of Florida, Gainesville, FL, USA.
University of Florida · USUniversity of Alabama at Birmingham · USInstitute on Aging · US

Funding

Ethnic Differences in Responses to Painful StimuliR37AG033906 · NIA · UNIVERSITY OF FLORIDA · PI FILLINGIM, ROGER B · 2014 to 2023
$12.9M
Health Disparities in Osteoarthritis: Biological Aging, Stress, and Pain - Modulation by Resilience FactorsR01AG054370 · NIA · UNIVERSITY OF FLORIDA · PI SIBILLE, KIMBERLY THERESA · 2016 to 2020
$3.4M
the Integrative and Multidisciplinary Pain and Aging Research Training (IMPART) ProgramT32AG049673 · NIA · UNIVERSITY OF FLORIDA · PI FILLINGIM, ROGER B · 2015 to 2024
$3.2M
Contributions of biopsychosocial factors in sickle cell disease painK01HL153210 · NHLBI · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI ROACH, KEESHA L. · 2020 to 2023
$537k
Investigating Movement-evoked Pain in osteoArthritic Conditions (IMPACT): An Observational Study to Inform Culturally-Tailored Intervention DevelopmentK23AR076463 · NIAMS · UNIVERSITY OF FLORIDA · PI BOOKER, STAJA · 2020 to 2022
$379k
NHLBI NIH HHS K01 HL153210NIAMS NIH HHS K23 AR076463NIA NIH HHS R01 AG054370NIA NIH HHS R37 AG033906NIA NIH HHS T32 AG049673NIMHD NIH HHS L60 MD014496
6 · The paper itself

Abstract

backgroundPain is the hallmark symptom of knee osteoarthritis (OA), and varies widely across individuals. Previous research has demonstrated both fluctuating and stable pain trajectories in knee OA using various time periods. Changes in pain assessed quarterly (i.e. 3-month intervals) in knee OA are relatively unknown. The current study aimed to investigate temporal variations in pain over a one and a half year period (18 months) based on quarterly characteristic pain assessments, and to examine differences in pain patterns by sociodemographic and baseline pain characteristics.

methodsThe sample included a prospective cohort of 188 participants (mean age 58 years; 63% female; 52% non-Hispanic Black) with or at risk for knee OA from an ongoing multisite investigation of ethnic/race group differences. Knee pain intensity was self-reported at baseline and quarterly over an18-month period. Baseline pain assessment also included frequency, duration, and total number of pain sites. Group-based trajectory modeling was used to identify distinct pain trajectories. Multinomial logistic regression was used to examine associations between sociodemographic characteristics, risk factors, and pain trajectory groups.

resultsPain trajectories were relatively stable among a sample of adults with knee pain. Four distinct pain trajectories emerged in the overall sample, with the largest proportion of participants (35.1%) classified in the moderate-high pain group. There were significant relationships between age, education, income, ethnicity/race and trajectory group; with younger, less educated, lower income, and non-Hispanic Black participants had a greater representation in the highest pain trajectory group.

conclusionsPain remained stable across a one and a half-year period in adults with or at risk for knee osteoarthritis, based on quarterly assessments. Certain sociodemographic variables (e.g. ethnicity/race, education, income, age) may contribute to an increased risk of experiencing greater pain.

Indexed as

Osteoarthritis, KneeAdultBlack or African AmericanDisease ProgressionFemaleHumansMaleMiddle AgedPainProspective StudiesChronic painEthnicity/raceHealth disparityKnee jointOsteoarthritisPain trajectory

Identifiers

PMID33952243
PMCPMC8101224
OpenAlexW3157891307

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.