Observational studyBMC cardiovascular disorders2021
Prognosis and management of new-onset atrial fibrillation in critically ill patients.
Observational study in BMC cardiovascular disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Magnesium prophylaxis of new-onset atrial fibrillation: A systematic review and meta-analysis.PloS one · 2023Pooled it
- The prognostic value of hemoglobin-to-albumin ratio in critically ill patients with atrial fibrillation: A retrospective cohort study.Medicine · 2026Article
- Clinical Profiles of Hospitalized Middle Eastern Patients With Nonvalvular Atrial Fibrillation: Analysis From the JoFib Study.International journal of vascular medicine · 2026Article
- Development and validation of a machine learning model integrating BUN/Cr ratio for mortality prediction in critically ill atrial fibrillation patients.Scientific reports · 2025Article
- Association between heart rate fluctuation and mortality in intensive care patients with atrial fibrillation.Scientific reports · 2025Article
- Atrial fibrillation in critical illness: state of the art.Intensive care medicine · 2025Review
- Safety of human serum albumin infusion in heart failure patients with hypoproteinemia: a propensity score-matched analysis.Clinics (Sao Paulo, Brazil) · 2025Article
- Research priorities for the study of atrial fibrillation during acute and critical illness: recommendations from the Symposium on Atrial Fibrillation in Acute and Critical Care.BMC proceedings · 2024Article
- A Predictive Nomogram of In-Hospital Mortality After 48 h for Atrial Fibrillation Patients in the Coronary Care Unit.Clinical cardiology · 2024Article
- Article
- New-onset atrial fibrillation among COVID-19 patients: A narrative review.World journal of critical care medicine · 2023Review
- The Year 2022 in Cardiovascular Diseases-Clinics and practice · 2023Article
- Atrial fibrillation is a risk factor for major adverse cardiovascular events in COVID-19.International journal of cardiology. Heart & vasculature · 2022Article
- Association between Anemia and New-Onset Atrial Fibrillation in Critically Ill Patients in the Intensive Care Unit: A Retrospective Cohort Analysis.Clinics and practice · 2022Article
- Development of a Risk Prediction Model for New Episodes of Atrial Fibrillation in Medical-Surgical Critically Ill Patients Using the AmsterdamUMCdb.Frontiers in cardiovascular medicine · 2022Article
- Incidence and Clinical Outcomes of New-Onset Atrial Fibrillation in Critically lll Patients with COVID-19: A Multicenter Cohort Study - New-Onset Atrial Fibrillation and COVID-19.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe prognosis of new-onset atrial fibrillation (AF) compared with that of preexisting and non-AF remains controversial. The purpose of this study was to evaluate the effect of new-onset AF compared with preexisting and non-AF on hospital and 90-day mortality.
methodsA retrospective cohort study was performed using data obtained from the Medical Information Mart for Intensive Care III database. The primary outcome was 90-day mortality. Secondary outcomes included hospital mortality, hospital and intensive care unit (ICU) length of stay, and acute kidney injury. Logistic and Cox regression analyses were performed to evaluate the relationship between new-onset AF and study outcomes.
resultsA total of 38,159 adult patients were included in the study. The incidence of new-onset AF was 9.4%. Ninety-day mortality, hospital mortality, and hospital and ICU length of stay in patients with new-onset and preexisting AF were significantly increased compared with those in patients with non-AF patients (all p < 0.001). After adjusting for patient characteristics, new-onset AF remained associated with increased 90-day mortality compared with non-AF (adjusted hazard ratio (HR) 1.37, 95% confidence interval (CI) 1.26 to 1.50; p < 0.01) and preexisting AF (adjusted HR 1.12; 95%-CI 1.02 to 1.23; p < 0.01). Patients in the surgical intensive care unit (SICU) had significantly higher 90-day mortality than patients in the coronary care unit (adjusted HR 1.30; 95% CI 1.31 to 1.51; p < 0.001).
conclusionsCritically ill patients with new-onset AF have significantly increased hospital and 90-day mortality compared with patients with preexisting and non-AF. Patients with new-onset AF in the ICU, especially those in the SICU, require robust management measures.
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