Evidence map›Paper›PMID 33951971›Full record

ArticleInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences2022

Pipeline embolization of proximal middle cerebral artery aneurysms: A multicenter cohort study.

David C Lauzier, Brandon K Root, Yasha Kayan, Josser E Delgado Almandoz, Joshua W Osbun, Arindam R Chatterjee, Kayla L Whaley, Megan E Tipps, Christopher J Moran, Akash P Kansagra

Abstract readMulticenter Study
In one paragraph

Article in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

David C LauzierMallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, USA.ORCID https://orcid.org/0000-0003-2825-3360
Brandon K RootMallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, USA.
Yasha KayanDivision of Neurointerventional Radiology, Neuroscience Institute, Abbott Northwestern Hospital, Minneapolis, MN, USA.ORCID https://orcid.org/0000-0002-7747-0188
Josser E Delgado AlmandozDivision of Neurointerventional Radiology, Neuroscience Institute, Abbott Northwestern Hospital, Minneapolis, MN, USA.
Joshua W OsbunMallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, USA.
Arindam R ChatterjeeMallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, USA.
Kayla L WhaleyNeuroscience Institute, Abbott Northwestern Hospital, Minneapolis, MN, USA.
Megan E TippsNeuroscience Institute, Abbott Northwestern Hospital, Minneapolis, MN, USA.
Christopher J MoranMallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, USA.
Akash P KansagraMallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeFlow diversion of aneurysms located in the M1 segment and middle cerebral artery bifurcation with Pipeline embolization device is sometimes performed, but further study is needed to support its regular use in aneurysm treatment. Here, we report measures of safety and efficacy for Pipeline embolization in the proximal middle cerebral artery in a multi-center cohort. MATERIALS AND

methodsClinical and angiographic data of eligible patients were retrospectively obtained from participating centers and assessed for key clinical and angiographic outcomes. Additional details were extracted for patients with complications.

resultsIn our multi-center cohort, complete aneurysm occlusion was achieved in 71% (17/24) of treated aneurysms. There were no deaths or disabling strokes, but non-disabling ischemic strokes occurred in 8% (2/24) of patients. For aneurysms in the M1 segment, complete aneurysm occlusion was observed in 75% (12/16) of aneurysms, aneurysm volume reduction was observed in 100% (16/16) of aneurysms, and non-disabling ischemic strokes occurred in 13% (2/16) of patients. For aneurysms at the middle cerebral artery bifurcation, complete aneurysm occlusion was observed in 63% (5/8) of aneurysms, aneurysm volume reduction occurred in 88% (7/8) of aneurysms, and ischemic or hemorrhagic complications occurred in 0% (0/8) of patients.

conclusionPipeline embolization of cerebral aneurysms in the M1 segment and middle cerebral artery bifurcation demonstrated a 71% rate of complete aneurysm occlusion. There were no deaths or disabling strokes, but there was an 8% rate of non-disabling ischemic strokes.

Indexed as

Embolization, TherapeuticEndovascular ProceduresIntracranial AneurysmCerebral AngiographyCohort StudiesHumansRetrospective StudiesTreatment OutcomeaneurysmendovascularMiddle cerebral arterypipeline embolization device

Identifiers

PMID33951971
PMCPMC8905083

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.