Evidence map›Paper›PMID 33951338›Full record

ArticleUnited European gastroenterology journal2021

Morbid obesity but not obesity is associated with increased mortality in patients undergoing endoscopic retrograde cholangiopancreatography: A national cohort study.

Bing Chen, Chia-Hung Yo, Ramya Patel, Bolun Liu, Ke-Ying Su, Wan-Ting Hsu, Chien-Chang Lee

Abstract read
In one paragraph

Article in United European gastroenterology journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
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  5. Guidelines, top-notch science & social media-Jump on the bandwagon.United European gastroenterology journal · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Bing ChenDepartment of Medicine, Mount Sinai Morningside and Mount Sinai West, New York City, New York, USA.ORCID 0000-0002-6058-9529
Chia-Hung YoDepartment of Emergency Medicine, Far Eastern Memorial Hospital, New Taipei City, Taiwan.ORCID 0000-0001-8300-8291
Ramya PatelDepartment of Medicine, Mount Sinai Morningside and Mount Sinai West, New York City, New York, USA.ORCID 0000-0003-4854-7913
Bolun LiuDepartment of Medicine, John H. Stroger, Jr. Hospital of Cook County, Chicago, Illinois, USA.ORCID 0000-0001-8508-9371
Ke-Ying SuDepartment of Emergency Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
Wan-Ting HsuDepartment of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA.ORCID 0000-0002-6677-0951
Chien-Chang LeeDepartment of Emergency Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.ORCID 0000-0002-1243-2463

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe relationship between body weight and outcomes of endoscopic retrograde cholangiopancreatography (ERCP) is unclear.

objectivesThis study aimed to investigate the impact of obesity and morbid obesity on mortality and ERCP-related complications in patients who underwent ERCP.

methodsWe conducted a US population-based retrospective cohort study using the Nationwide Readmissions Databases (2013-2014). A total of 159,264 eligible patients who underwent ERCP were identified, of which 137,158 (86.12%) were normal weight, 12,522 (7.86%) were obese, and 9584 (6.02%) were morbidly obese. The primary outcome was in-hospital mortality. The secondary outcomes were the length of stay, total cost, and ERCP-related complications. Multivariate analysis and propensity score (PS) matching analysis were performed. The analysis was repeated in a restricted cohort to eliminate confounders.

resultsPatients with morbid obesity, as compared to normal-weight patients, were associated with a significantly higher in-hospital mortality (hazard ratio [HR]: 5.54; 95% confidence interval [CI]: 1.23-25.04). Obese patients were not associated with significantly different mortality comparing to normal weight (HR: 1.00; 95% CI: 0.14-7.12). Patients with morbid obesity were also found to have an increased length of hospital stay and total cost. The rate of ERCP-related complications was comparable among the three groups except for a higher cholecystitis rate after ERCP in obese patients.

conclusionsMorbid obesity but not obesity was associated with increased mortality, length of stay, and total cost in patients undergoing ERCP.

Indexed as

Hospital MortalityBody Mass IndexCause of DeathCholangiopancreatography, Endoscopic RetrogradeConfidence IntervalsDatabases, FactualFemaleHumansLength of StayMaleMiddle AgedMultivariate AnalysisObesityObesity, MorbidPatient ReadmissionPropensity ScoreERCPERCP-related complicationsmorbid obesitymortalityobesity

Identifiers

PMID33951338
PMCPMC8259364

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.