Evidence map›Paper›PMID 33951192›Full record

ArticleJournal of forensic sciences2021

Fentanyl-related substance scheduling as an effective drug control strategy.

Victor W Weedn, Mary Elizabeth Zaney, Bruce McCord, Ira Lurie, Andrew Baker

Open access · hybridAbstract read
In one paragraph

Article in Journal of forensic sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Pediatric Overdose Deaths Increase as the Fourth Wave of the Opioid Epidemic Creates a Perfect Storm.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2025
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. U.S. policy responses to xylazine: Thinking bigger.The International journal on drug policy · 2024
    Article
  10. Article
  11. Interpol Review of Drug Analysis 2019-2022.Forensic science international. Synergy · 2023
    Review
  12. Review
  13. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Victor W WeednDepartment of Forensic Sciences, George Washington University, Washington, DC, USA.
Mary Elizabeth ZaneyMiami-Dade County Medical Examiner Department, Miami, FL, USA.
Bruce McCordDepartment of Chemistry and Biochemistry, Florida International University, Miami, FL, USA.
Ira LurieDepartment of Forensic Sciences, George Washington University, Washington, DC, USA.
Andrew BakerHennepin County Medical Examiner's Office, Minneapolis, MN, USA.
George Washington University · USFlorida International University · USHennepin County · USMiami Dade College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fentanyl is now the primary driver of the current opioid crisis. Fentanyl and its analogues are subject to the Controlled Substances Act of 1970, the Controlled Substances Analogue Enforcement Act of 1986 (Federal Analogue Act), state laws, international treaties, and the laws of foreign countries. The appearance of novel psychoactive substances led to further legislative developments in scheduling. New fentanyl analogues proliferated in a manner previously unseen since about 2016. Overdose deaths of these fentanyl analogues prompted the Drug Enforcement Administration to reactively emergency schedule each new fentanyl analogue as it appeared. The international community also acted. Finally, on February 6, 2018, a proactive temporary (emergency) class-wide scheduling of fentanyl-related substances was implemented based upon the fentanyl core structure to save lives. This action spurred a similar action in China. Fentanyl analogues fell dramatically in the marketplace, despite further increases in fentanyl itself. Congress temporarily extended this scheduling, but it will soon expire. Opposition to permanent class-wide was lodged due to concerns over law enforcement overreach, inadequate Health and Human Services input, and hindrance of research. This paper reaffirms the importance of a class-based scheduling strategy while also arguing for increased research of schedule I controlled substances.

Indexed as

Analgesics, OpioidDrug and Narcotic ControlFentanylHumansIllicit DrugsOpioid EpidemicUnited StatesAnalgesics, OpioidFentanylIllicit Drugsclass-wide schedulingControlled Substances Actfentanyl analoguesfentanyl-related substancesschedulingtemporary scheduling

Identifiers

PMID33951192
PMCPMC8360110
OpenAlexW3159594188

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.