SynthesisMedicine2021
Assessment of basic reproductive number for COVID-19 at global level: A meta-analysis.
Synthesis in Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Reliability of Early Estimates of the Basic Reproduction Number of COVID-19: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2022Pooled it
- Efficacy of Ivermectin, Chloroquine/Hydroxychloroquine, and Azithromycin in Managing COVID-19: A Systematic Review of Phase III Clinical Trials.Biomedicines · 2024Review
- The relationship between controllability, optimal testing resource allocation, and incubation-latent period mismatch as revealed by COVID-19.Infectious Disease Modelling · 2023Article
- Modeling Consequences of COVID-19 and Assessing Its Epidemiological Parameters: A System Dynamics Approach.Healthcare (Basel, Switzerland) · 2023Article
- Cerebrovascular disease in COVID-19: a systematic review and meta-analysis.Le infezioni in medicina · 2023Review
- Effectiveness of the BNT162b2 (Pfizer-BioNTech) Vaccine in Children and Adolescents: A Systematic Review and Meta-Analysis.Vaccines · 2022Review
- Re-Starting the Cruise Sector during the COVID-19 Pandemic in Greece: Assessing Effectiveness of Port Contingency Planning.International journal of environmental research and public health · 2022Article
- Refining Reproduction Number Estimates to Account for Unobserved Generations of Infection in Emerging Epidemics.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022Article
- Maximal reproduction number estimation and identification of transmission rate from the first inflection point of new infectious cases waves: COVID-19 outbreak example.Mathematics and computers in simulation · 2022Article
- Detection, prevention and treatment of COVID-19 and opportunities for nanobiotechnology.View (Beijing, China) · 2022Review
- Modeling nosocomial infection of COVID-19 transmission dynamics.Results in physics · 2022Article
- Intestinal viral infections of nSARS-CoV2 in the Indian community: Risk of virus spread in India.Journal of medical virology · 2022Review
- Article
- A review on COVID-19 transmission, epidemiological features, prevention and vaccination.Medical review (2021) · 2022Review
- Bayesian Inference of State-Level COVID-19 Basic Reproduction Numbers across the United States.Viruses · 2022Article
- Characteristics of COVID-19 Patients With SARS-CoV-2 Positivity in Feces.Frontiers in cellular and infection microbiology · 2022Article
- Polymeric Materials as Potential Inhibitors Against SARS-CoV-2.Journal of polymers and the environment · 2022Review
- The COVID-19 Vaccines: A Description of Adverse Events of Reactions Reported in Kansas.Kansas journal of medicine · 2022Article
- Underdetection in a stochastic SIR model for the analysis of the COVID-19 Italian epidemic.Stochastic environmental research and risk assessment : research journal · 2022Article
- Identification of COVID-19 spread mechanisms based on first-wave data, simulation models, and evolutionary algorithms.PloS one · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
backgroundThere are large knowledge gaps regarding how transmission of 2019 novel coronavirus disease (COVID-19) occurred in different settings across the world. This study aims to summarize basic reproduction number (R0) data and provide clues for designing prevention and control measures.
methodsSeveral databases and preprint platforms were retrieved for literature reporting R0 values of COVID-19. The analysis was stratified by the prespecified modeling method to make the R0 values comparable, and by country/region to explore whether R0 estimates differed across the world. The average R0 values were pooled using a random-effects model.
resultsWe identified 185 unique articles, yielding 43 articles for analysis. The selected studies covered 5 countries from Asia, 5 countries from Europe, 12 countries from Africa, and 1 from North America, South America, and Australia each. Exponential growth rate model was most favored by researchers. The pooled global R0 was 4.08 (95% CI, 3.09-5.39). The R0 estimates for new and shifting epicenters were comparable or even higher than that for the original epicenter Wuhan, China.
conclusionsThe high R0 values suggest that an extraordinary combination of control measures is needed for halting COVID-19.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.