Evidence map›Paper›PMID 33950837›Full record

ArticleIEEE transactions on medical imaging2021

On Hallucinations in Tomographic Image Reconstruction.

Sayantan Bhadra, Varun A Kelkar, Frank J Brooks, Mark A Anastasio

Abstract read
In one paragraph

Article in IEEE transactions on medical imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
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  5. Review
  6. Article
  7. Article
  8. On Hallucinations in Artificial Intelligence-Generated Content for Nuclear Medicine Imaging (the DREAM Report).Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
    Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
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  16. Survey of Deep Learning and Physics-Based Approaches in Computational Wave Imaging.Proceedings of the IEEE. Institute of Electrical and Electronics Engineers · 2025
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sayantan Bhadra
Varun A Kelkar
Frank J Brooks
Mark A Anastasio

Funding

Safe, rapid & functional pediatric brain imaging using photoacoustic computed tomographyR01NS102213 · NINDS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI ANASTASIO, MARK A, WANG, LIHONG · 2017 to 2021
$3.0M
AN ENABLING TECHNOLOGY FOR PRECLINICAL X-RAY IMAGING OF BIOMATERIALS IN-VIVOR01EB020604 · NIBIB · WASHINGTON UNIVERSITY · PI ANASTASIO, MARK A, BREY, ERIC M · 2016 to 2019
$2.3M
Advanced image reconstruction for accurate and high-resolution breast ultrasound tomographyR01EB028652 · NIBIB · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI ANASTASIO, MARK A, DURIC, NEBOJSA · 2019 to 2022
$2.2M
DEVELOPMENT OF A RAPID METHOD FOR IMAGING REGIONAL VENTILATION IN SMALL ANIMALS W/O CONTRAST AGENTSR01EB023045 · NIBIB · WASHINGTON UNIVERSITY · PI ANASTASIO, MARK A · 2017 to 2020
$1.7M
NIBIB NIH HHS R01 EB020604NIBIB NIH HHS R01 EB023045NIBIB NIH HHS R01 EB028652NINDS NIH HHS R01 NS102213
6 · The paper itself

Abstract

Tomographic image reconstruction is generally an ill-posed linear inverse problem. Such ill-posed inverse problems are typically regularized using prior knowledge of the sought-after object property. Recently, deep neural networks have been actively investigated for regularizing image reconstruction problems by learning a prior for the object properties from training images. However, an analysis of the prior information learned by these deep networks and their ability to generalize to data that may lie outside the training distribution is still being explored. An inaccurate prior might lead to false structures being hallucinated in the reconstructed image and that is a cause for serious concern in medical imaging. In this work, we propose to illustrate the effect of the prior imposed by a reconstruction method by decomposing the image estimate into generalized measurement and null components. The concept of a hallucination map is introduced for the general purpose of understanding the effect of the prior in regularized reconstruction methods. Numerical studies are conducted corresponding to a stylized tomographic imaging modality. The behavior of different reconstruction methods under the proposed formalism is discussed with the help of the numerical studies.

Indexed as

Image Processing, Computer-AssistedTomography, X-Ray ComputedHallucinationsHumansNeural Networks, Computer

Identifiers

PMID33950837
PMCPMC8673588

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.