Evidence map›Paper›PMID 33950834›Full record

ArticleeLife2021

The LRR-TM protein PAN-1 interacts with MYRF to promote its nuclear translocation in synaptic remodeling.

Shi-Li Xia, Meng Li, Bing Chen, Chao Wang, Yong-Hong Yan, Meng-Qiu Dong, Yingchuan B Qi

Open access · goldAbstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. A molecular timer couples organism-wide temporal identity to developmental checkpoints.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  3. Review
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  6. Non-apoptotic death of thebioRxiv : the preprint server for biology · 2025
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  8. Analysis ofComputational and structural biotechnology journal · 2024
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  9. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Shi-Li Xia *School of Life Science and Technology, ShanghaiTech University, Shanghai, China.
Meng Li *School of Life Science and Technology, ShanghaiTech University, Shanghai, China.
Bing ChenCollege of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou, China.
Chao WangCollege of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou, China.
Yong-Hong YanNational Institute of Biological Sciences, Beijing, China.
Meng-Qiu DongNational Institute of Biological Sciences, Beijing, China.ORCID 0000-0002-6094-1182
Yingchuan B QiSchool of Life Science and Technology, ShanghaiTech University, Shanghai, China.ORCID 0000-0002-4267-4770
Hangzhou Normal University · CNNational Institute of Biological Sciences, Beijing · CN

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
NIH HHS P40 OD010440
6 · The paper itself

Abstract

Neural circuits develop through a plastic phase orchestrated by genetic programs and environmental signals. We have identified a leucine-rich-repeat domain transmembrane protein PAN-1 as a factor required for synaptic rewiring in

Indexed as

AnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsCell MembraneCRISPR-Cas SystemsHEK293 CellsHumansProtein DomainsProtein TransportSynapsesTranscription FactorsCaenorhabditis elegans ProteinsPAN-1 protein, C elegansTranscription FactorsC. elegansdevelopmental biologylaval developmentmembrane-boundMYRFpan-1synaptic rewiringtranscription factors

Identifiers

PMID33950834
PMCPMC8099431
OpenAlexW3157870862

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.