ArticleMethods in molecular biology (Clifton, N.J.)2021
Quantitative Proteome Data Analysis of Tandem Mass Tags Labeled Samples.
Article in Methods in molecular biology (Clifton, N.J.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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Who cites it
3 citing papers in PubMed.
- S100A9 as a potential novel target for experimental autoimmune cystitis and interstitial cystitis/bladder pain syndrome.Biomarker research · 2025Article
- Review
- Quantitative Proteomics and Molecular Mechanisms of Non-Hodgkin Lymphoma Mice Treated with Incomptine A, Part II.Pharmaceuticals (Basel, Switzerland) · 2025Article
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Authors and funding
3 authors.
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Abstract
In mass spectrometry-based proteomics, relative quantitative approaches enable differential protein abundance analysis. Isobaric labeling strategies, such as tandem mass tags (TMT), provide simultaneous quantification of several samples (e.g., up to 16 using 16plex TMTpro) owing to its multiplexing capability. This technology improves sample throughput and thereby minimizes both measurement time and overall experimental variation. However, TMT-based MS data processing and statistical analysis are probably the crucial parts of this pipeline to obtain reliable, plausible, and significantly quantified results. Here, we provide a step-by-step guide to the analysis and evaluation of TMT quantitative proteomics data.
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Registered trials
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