Evidence map›Paper›PMID 33950408›Full record

ReviewMolecular biology reports2021

CRISPR-Cas technology based genome editing for modification of salinity stress tolerance responses in rice (Oryza sativa L.).

Ibrahim Khan, Sikandar Khan, Yong Zhang, Jianping Zhou, Maryam Akhoundian, Sohail Ahmad Jan

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular biology reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 38 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Overexpression ofFrontiers in plant science · 2025
    Article
  8. Review
  9. RNAi-Mediated Suppression ofInternational journal of molecular sciences · 2024
    Article
  10. Review
  11. Article
  12. Review
  13. Genome-wide annotation and expression analysis ofFrontiers in plant science · 2023
    Article
  14. Genome and Transcriptome-Wide Analysis ofInternational journal of molecular sciences · 2022
    Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Ibrahim KhanDepartment of Biotechnology, School of Life Sciences and Technology, University of Electronic Science and Technology of China, Chengdu, China.
Sikandar KhanDepartment of Biotechnology, Shaheed Benazir Bhutto University, Sheringal, K.P, Pakistan. sikandar@sbbu.edu.pk.ORCID http://orcid.org/0000-0003-1596-6580
Yong ZhangDepartment of Biotechnology, School of Life Sciences and Technology, University of Electronic Science and Technology of China, Chengdu, China. zhangyong916@uestc.edu.cn.
Jianping ZhouDepartment of Biotechnology, School of Life Sciences and Technology, University of Electronic Science and Technology of China, Chengdu, China.
Maryam AkhoundianDepartment of Marine Biology, Faculty of Marine Science, University of Mazandaran, Babolsar, Iran.
Sohail Ahmad JanDepartment of Bioinformatics and Biosciences, Capital University of Science and Technology, Islamabad, Pakistan.
University of Electronic Science and Technology of China · CNCapital University of Science and Technology · PKShaheed Benazir Bhutto University · PKUniversity of Mazandaran · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clustered regularly interspaced short palindromic repeats (CRISPR)-CRISPR associated protein (Cas) technology is an effective tool for site-specific genome editing, used to precisely induce mutagenesis in different plant species including rice. Salinity is one of the most stressful environmental constraints affecting agricultural productivity worldwide. As plant adaptation to salinity stress is under polygenic control therefore, 51 rice genes have been identified that play crucial role in response to salinity. This review offers an exclusive overview of genes identified in rice genome for salinity stress tolerance. This will provide an idea to produce rice varieties with enhanced salt tolerance using the potentially efficient CRISPR-Cas technology. Several undesirable off-target effects of CRISPR-Cas technology and their possible solutions have also been highlighted.

Indexed as

CRISPR-Cas SystemsGene EditingSalt ToleranceOryzaPlant BreedingAbiotic stressesCas9Cpf1CRISPRGenome editingSalinity

Identifiers

PMID33950408
OpenAlexW3158970396

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.