Evidence map›Paper›PMID 33950366›Full record

ArticlePlant foods for human nutrition (Dordrecht, Netherlands)2021

Synthesis of Resveratrol Loaded Hybrid Silica-PAMAM Dendrimer Nanoparticles With Emphases on Inducible Nitric Oxide Synthase and Cytotoxicity.

Ceren Kececiler-Emir, Esra Ilhan-Ayisigi, Cigdem Celen-Erden, Ayse Nalbantsoy, Ozlem Yesil-Celiktas

Abstract read
PubMed Publisher
In one paragraph

Article in Plant foods for human nutrition (Dordrecht, Netherlands), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
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  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ceren Kececiler-EmirBioengineering Department, Faculty of Chemical and Metallurgical Engineering, Yıldız Technical University, 34210, Istanbul, Turkey.
Esra Ilhan-AyisigiDepartment of Bioengineering, Faculty of Engineering, Ege University, 35100, Izmir, Turkey.
Cigdem Celen-ErdenDepartment of Bioengineering, Faculty of Engineering, Ege University, 35100, Izmir, Turkey.
Ayse NalbantsoyDepartment of Bioengineering, Faculty of Engineering, Ege University, 35100, Izmir, Turkey.
Ozlem Yesil-CeliktasDepartment of Bioengineering, Faculty of Engineering, Ege University, 35100, Izmir, Turkey. ozlem.yesil.celiktas@ege.edu.tr.ORCID http://orcid.org/0000-0003-4509-2212

Funding

Türkiye Bilimsel ve Teknolojik Araştirma Kurumu 1919B011400901
6 · The paper itself

Abstract

Resveratrol is a naturally occurring polyphenolic compound exhibiting therapeutic activities. However, the stability can be altered by UV light, pH and changes in temperature. Encapsulation would be an ideal strategy to improve the stability and bioavailability. Thus, trans-resveratrol (Res) was encapsulated within hybrid nanoparticles consisted with silica and G4 polyamidoamine dendrimer (PAMAM) by sol-gel method. The diameters of synthesized nanoparticles (NPs) were at a range of 212-574 nm and the encapsulation efficiency was 86 %. RAW 264.7 murine macrophage cell line induced with endotoxin/lipopolysaccharide was treated with free resveratrol and Res-loaded NPs for assessing inhibition of inducible nitric oxide synthase (iNOS), where IC

Indexed as

DendrimersNanoparticlesAnimalsMiceNitric OxideNitric Oxide Synthase Type IIResveratrolSilicon DioxideDendrimersNitric OxideNitric Oxide Synthase Type IIPAMAM StarburstResveratrolSilicon DioxideCytotoxicityiNOSNanoparticlePAMAMResveratrolSol‐gel

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.