Evidence map›Paper›PMID 33950327›Full record

ArticleMaternal and child health journal2021

Factors Associated with Infant Feeding Choices Among Women with HIV in Botswana.

Aamirah Mussa, Henock B Taddese, Ekaterina Maslova, Gbolahan Ajibola, Joseph Makhema, Roger L Shapiro, Shahin Lockman, Kathleen M Powis

Open access · greenAbstract read
In one paragraph

Article in Maternal and child health journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 60% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Aamirah MussaBotswana-Harvard AIDS Institute Partnership, Gaborone, Botswana. amussa@bhp.org.bw.ORCID http://orcid.org/0000-0001-9152-5686
Henock B TaddeseSchool of Public Health, Imperial College London, London, UK.
Ekaterina MaslovaSchool of Public Health, Imperial College London, London, UK.
Gbolahan AjibolaBotswana-Harvard AIDS Institute Partnership, Gaborone, Botswana.
Joseph MakhemaBotswana-Harvard AIDS Institute Partnership, Gaborone, Botswana.
Roger L ShapiroBotswana-Harvard AIDS Institute Partnership, Gaborone, Botswana.
Shahin LockmanBotswana-Harvard AIDS Institute Partnership, Gaborone, Botswana.
Kathleen M PowisBotswana-Harvard AIDS Institute Partnership, Gaborone, Botswana.
Botswana Harvard AIDS Institute Partnership · BWHarvard University · USImperial College London · GBBrigham and Women's Hospital · US

Funding

Short Breastfeeding and Cotrimoxazole among HIV-Exposed Infants in BotswanaR01HD061265 · NICHD · HARVARD SCHOOL OF PUBLIC HEALTH · PI LOCKMAN, SHAHIN, SHAPIRO, ROGER L · 2010 to 2015
$4.5M
Training in HIV Genomics, Treatment, and Cure Research in BotswanaD43TW009610 · FIC · THE BOTSWANA HARVARD HEALTH PARTNERSHIP · PI SHAHIN LOCKMAN, Joseph Moeketsi Makhema · 2013 to 2026
$4.4M
Botswana Birth Outcomes Surveillance ExtensionR01HD095766 · NICHD · HARVARD SCHOOL OF PUBLIC HEALTH · PI SHAPIRO, ROGER L · 2018 to 2022
$3.3M
FIC NIH HHS D43 TW009610NICHD NIH HHS R01 HD061265NICHD NIH HHS R01 HD095766NIH HHS R01 HD061265
6 · The paper itself

Abstract

introductionIn resource-constrained settings, infant feeding decisions among women with HIV (WHIV) must balance the risk of infant HIV acquisition from breastfeeding with increased mortality associated with formula feeding. WHO guidelines recommend countries principally promote a single feeding method for WHIV, either breastfeeding or formula feeding. In 2016, Botswana revised its policy of formula feeding for infants born to WHIV, instead promoting exclusive breastfeeding during the first 6 months of life.

methodsWe sought to understand factors influencing infant feeding choices among WHIV by administering a questionnaire to pregnant and postpartum WHIV (2013-2015) participating in a clinical trial in Botswana (the Mpepu Study). Logistic regression analyses were used to identify factors associated with infant feeding choices.

resultsOf 810 surveyed participants, 24.0% chose breastfeeding and 76.0% chose formula feeding. Women were more likely to choose formula feeding if advised by a health worker to formula feed (aOR 1.90; 95% CI 1.02-3.57) or if they harboured doubts about the potency of antiretroviral treatment (ART) to prevent infant HIV acquisition (aOR 9.06; 95% CI 4.78-17.17). Women who reported lack of confidence in preparing infant formula safely (aOR 0.09; 95% CI 0.04-0.19) or low concerns about infant HIV acquisition (aOR 0.35; 95% CI 0.22-0.55) were significantly less likely to formula feed. DISCUSSION: Perceptions about ART effectiveness, social circumstances and health worker recommendations were key influencers of infant feeding choices among WHIV. Health system factors and maternal education interventions represent ideal targets for any programmatic actions aiming to shape informed decision-making towards HIV-free survival of infants.

Indexed as

HIV InfectionsInfectious Disease Transmission, VerticalBotswanaBreast FeedingFemaleHumansInfantInfant FormulaPregnancyBreastfeedingFormula feedingHIVInfant feeding

Identifiers

PMID33950327
PMCPMC8355043
OpenAlexW3157131655

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.