Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
4 citing papers in PubMed, 9 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
22 authors at 4 institutions in 4 countries.
Tra Thi Huong Dinh *Laboratory Animal Resource Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.ORCID 0000-0003-1705-3865
Hiroyoshi Iseki *Laboratory Animal Resource Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.ORCID 0000-0001-5997-5564
Seiya Mizuno *Laboratory Animal Resource Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.ORCID 0000-0002-6740-5817
Saori Iijima-MizunoLaboratory Animal Resource Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Yoko TanimotoLaboratory Animal Resource Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.ORCID 0000-0002-0731-6134
Yoko DaitokuLaboratory Animal Resource Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Kanako KatoLaboratory Animal Resource Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Yuko HamadaLaboratory Animal Resource Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Ammar Shaker Hamed HasanLaboratory Animal Resource Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Hayate SuzukiLaboratory Animal Resource Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Kazuya MurataLaboratory Animal Resource Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.ORCID 0000-0002-3328-069X
Masafumi MurataniTransborder Medical Research Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Masatsugu EmaDepartment of Stem Cells and Human Disease Models, Research Center for Animal Life Science, Shiga University of Medical Science, Otsu, Japan.ORCID 0000-0002-6549-2611
Jun-Dal KimLife Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA), University of Tsukuba, Tsukuba, Japan.ORCID 0000-0002-7361-0999
Junji IshidaLife Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA), University of Tsukuba, Tsukuba, Japan.ORCID 0000-0002-4750-6354
Akiyoshi FukamizuLife Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA), University of Tsukuba, Tsukuba, Japan.ORCID 0000-0002-8786-6020
Mitsuyasu KatoTransborder Medical Research Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.ORCID 0000-0001-9905-2473
Satoru TakahashiLaboratory Animal Resource Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.ORCID 0000-0002-8540-7760
Ken-Ichi YagamiLaboratory Animal Resource Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Valerie WilsonMRC Centre for Regenerative Medicine, School of Biological Sciences, SCRM Building, The University of Edinburgh, Edinburgh, United Kingdom.ORCID 0000-0003-4182-5159
Ruth M ArkellJohn Curtin School of Medical Research, The Australian National University, Canberra, Australia.ORCID 0000-0002-6213-7323
Fumihiro SugiyamaLaboratory Animal Resource Center, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.ORCID 0000-0003-4744-3493
University of Tsukuba · JPAustralian National University · AUMRC Centre for Regenerative Medicine · GBShiga University of Medical Science · JP
Funding
Medical Research Council MR/K011200/1Medical Research Council MR/S008799/1
6 · The paper itself
Abstract
In vivo function of CDK5 and Abl enzyme substrate 2 (Cables2), belonging to the Cables protein family, is unknown. Here, we found that targeted disruption of the entire
Indexed as
Gene ExpressionSignal TransductionAnimalsCell Cycle ProteinsFemaleGastrulationMaleMiceMice, Inbred ICRPhenotypeRibosomal ProteinsTranscriptional ActivationTumor Suppressor Protein p53Up-RegulationCables2 protein, mouseCell Cycle ProteinsRibosomal Proteinsribosomal protein S21Trp53 protein, mouseTumor Suppressor Protein p53cables2developmental biologyembryonic lethalitygastrulationmousep53Rps21Wnt/beta-catenin
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.