Evidence map›Paper›PMID 33949893›Full record

ArticleEnvironmental health perspectives2021

Nitrate in Drinking Water during Pregnancy and Spontaneous Preterm Birth: A Retrospective Within-Mother Analysis in California.

Allison R Sherris, Michael Baiocchi, Scott Fendorf, Stephen P Luby, Wei Yang, Gary M Shaw

Open access · diamondAbstract read
In one paragraph

Article in Environmental health perspectives, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
8.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 80 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Water Fluoridation and Birth Outcomes in California.Environmental health perspectives · 2024
    Article
  8. Article
  9. Drinking Water Contaminant Concentrations and Birth Outcomes.Journal of policy analysis and management : [the journal of the Association for Public Policy Analysis and Management] · 2024
    Article
  10. Article
  11. How WIC Can Help Enhance Water Security for At-Risk Populations.Journal of the Academy of Nutrition and Dietetics · 2023
    Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Nitrate in Maternal Drinking Water during Pregnancy and Measures of Male Fecundity in Adult Sons.International journal of environmental research and public health · 2022
    Article
  18. Additives in Children's Nutrition-A Review of Current Events.International journal of environmental research and public health · 2022
    Review
  19. Article
  20. Drinking water nitrate and risk of pregnancy loss: a nationwide cohort study.Environmental health : a global access science source · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Allison R SherrisEmmett Interdisciplinary Program in Environment and Resources, Stanford University, Stanford, California, USA.
Michael BaiocchiDepartment of Epidemiology and Population Health, Stanford University, Stanford, California, USA.
Scott FendorfDepartment of Earth System Science, Stanford University, Stanford, California, USA.
Stephen P LubyDepartment of Medicine, Stanford University, Stanford, California, USA.
Wei YangDepartment of Pediatrics, Stanford University, Stanford, California, USA.
Gary M ShawDepartment of Pediatrics, Stanford University, Stanford, California, USA.
Stanford University · US

Funding

Pesticide Exposures and Risk of Preterm BirthR01HD075761 · NICHD · STANFORD UNIVERSITY · PI SHAW, GARY M · 2013 to 2016
$1.2M
NICHD NIH HHS R01 HD075761
6 · The paper itself

Abstract

backgroundNitrate is a widespread groundwater contaminant and a leading cause of drinking water quality violations in California. Associations between nitrate exposure and select adverse birth outcomes have been suggested, but few studies have examined gestational exposures to nitrate and risk of preterm birth (before 37 wk gestation).

objectiveWe investigated the association between elevated nitrate in drinking water and spontaneous preterm birth through a within-mother retrospective cohort study of births in California.

methodsWe acquired over 6 million birth certificate records linked with Office of Statewide Health Planning and Development hospital discharge data for California births from 2000-2011. We used public water system monitoring records to estimate nitrate concentrations in drinking water for each woman's residence during gestation. After exclusions, we constructed a sample of 1,443,318 consecutive sibling births in order to conduct a within-mother analysis. We used separate conditional logistic regression models to estimate the odds of preterm birth at 20-31 and 32-36 wk, respectively, among women whose nitrate exposure changed between consecutive pregnancies.

resultsSpontaneous preterm birth at 20-31 wk was increased in association with tap water nitrate concentrations during pregnancy of 5 to DISCUSSION: The results suggest that nitrate in drinking water is associated with increased odds of spontaneous preterm birth. Notably, we estimated modestly increased odds associated with tap water nitrate concentrations of 5 to

Indexed as

Drinking WaterNitratesPremature BirthCaliforniaFemaleHumansInfant, NewbornMothersPregnancyRetrospective StudiesDrinking WaterNitrates

Identifiers

PMID33949893
PMCPMC8098122
OpenAlexW3158791334

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.