ArticleJournal of the American Chemical Society2021
O-Heterocycle Synthesis via Intramolecular C-H Alkoxylation Catalyzed by Iron Acetylacetonate.
Article in Journal of the American Chemical Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 11 citations in OpenAlex.
- Iron-Catalyzed Intermolecular N-H Insertion Using Acceptor-Acceptor Carbenes Derived from Iodonium Ylides.Organic letters · 2025Article
- Efficient carbene transfer reactivity mediated by Fe(II) complexes supported by bulky alkoxides.Chemical communications (Cambridge, England) · 2024Article
- Manganese(III) complexes stabilized with N-heterocyclic carbene ligands for alcohol oxidation catalysis.Dalton transactions (Cambridge, England : 2003) · 2023Article
- Controlling Radical-Type Single-Electron Elementary Steps in Catalysis with Redox-Active Ligands and Substrates.JACS Au · 2021Review
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
Intramolecular alkoxylation of C-H bonds can rapidly introduce structural and functional group complexities into seemingly simple or inert precursors. The transformation is particularly important due to the ubiquitous presence of tetrahydrofuran (THF) motifs as fundamental building blocks in a wide range of pharmaceuticals, agrochemicals, and natural products. Despite the various synthetic methodologies known for generating functionalized THFs, most show limited functional group tolerance and lack demonstration for the preparation of spiro or fused bi- and tricyclic ether units prevalent in molecules for pharmacological purposes. Herein we report an intramolecular C-H alkoxylation to furnish oxacycles from easily prepared α-diazo-β-ketoesters using commercially available iron acetylacetonate (Fe(acac)
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Registered trials
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