ArticleClinical and experimental dental research2021
Comparative barrier membrane degradation over time: Pericardium versus dermal membranes.
Article in Clinical and experimental dental research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- Impact of regenerative procedure on the healing process following surgical root canal treatment: A systematic review and meta-analysis.PloS one · 2025Pooled it
- Effect of Different Membranes on Vertical Bone Regeneration: A Systematic Review and Network Meta-Analysis.BioMed research international · 2022Pooled it
- Membrane Fixation and Graft Persistence in Pre-Extraction Buccal Overbuilding: A Split-Mouth Histological Study in Dogs.Dentistry journal · 2026Article
- Comparative mechanical analysis of collagen membranes derived from different tissues in an in vitro model simulating membrane-stabilized horizontal GBR.BMC oral health · 2026Article
- Comparison of physical, mechanical and biological properties of a porcine urinary bladder acellular matrix collagen membrane with six other collagen membranes of animal origin.BMC oral health · 2026Article
- Horizontal Bone Augmentation with Natural Collagen Porcine Pericardium Membranes: A Prospective Cohort Study.Medicina (Kaunas, Lithuania) · 2025Article
- In Vitro Degradation of Collagen-Based Membranes for Guided Bone Regeneration After Zn-Ions or Doxycycline Functionalization.Polymers · 2024Article
- Article
- Horizontal GBR with anorganic equine bone combined with a customized titanium mesh.Clinical case reports · 2024Article
- Biomimetic Collagen Membranes as Drug Carriers of Geranylgeraniol to Counteract the Effect of Zoledronate.Biomimetics (Basel, Switzerland) · 2023Article
- Characterization of Polyvinyl Alcohol-Collagen-Hydroxyapatite Composite Membrane from Lates calcarifer Scales for Guided Tissue and Bone Regeneration.European journal of dentistry · 2023Article
- Comparison of the Eggshell and the Porcine Pericardium Membranes for Guided Tissue Regeneration Applications.Biomedicines · 2023Article
- Physical, mechanical, and biological properties of collagen membranes for guided bone regeneration: a comparative in vitro study.BMC oral health · 2023Article
- A Synthetic Bio-Absorbable Membrane in Guided Bone Regeneration in Dehiscence-Type Defects: An Experimental In Vivo Investigation in Dogs.Bioengineering (Basel, Switzerland) · 2023Article
- Occlusive and Proliferative Properties of Different Collagen Membranes-An In Vitro Study.Materials (Basel, Switzerland) · 2023Article
- Efficiency analysis of commercial polymeric membranes for bone regeneration in rat cranial defects.Acta cirurgica brasileira · 2023Article
- Microtomographic reconstruction of mandibular defects treated with xenografts and collagen-based membranes: A pre-clinical minipig model.Medicina oral, patologia oral y cirugia bucal · 2021Article
- Comparative barrier membrane degradation over time: Pericardium versus dermal membranes.Clinical and experimental dental research · 2021Article
- The Collagen Origin Influences the Degradation Kinetics of Guided Bone Regeneration Membranes.Polymers · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 6 institutions in 6 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe effectiveness of GBR procedures for the reconstruction of periodontal defects has been well documented. The objective of this investigation was to evaluate the degradation kinetics and biocompatibility of two resorbable collagen membranes in conjunction with a bovine xenograft material. MATERIALS AND
methodsLower premolars and first molars were extracted from 18 male Yucatan minipigs. After 4 months of healing, standardized semi-saddle defects were created (12 mm × 8 mm × 8 mm [l˙̇ × W˙ × d]), with 10 mm between adjacent defects. The defects were filled with a bovine xenograft and covered with a either the bilayer collagen membrane (control) or the porcine pericardium-derived collagen membrane (test). Histological analysis was performed after 4, 8, and 12 weeks of healing and the amount of residual membrane evaluated. Non-inferiority was calculated using the Brunner-Langer mixed regression model.
resultsHistological analysis indicated the presence of residual membrane in both groups at all time points, with significant degradation noted in both groups at 12 weeks compared to 4 weeks (p = .017). No significant difference in ranked residual membrane scores between the control and test membranes was detected at any time point.
conclusionsThe pericardium-derived membrane was shown to be statistically non-inferior to the control membrane with respect to resorption kinetics and barrier function when utilized for guided bone regeneration in semi-saddle defects in minipigs. Further evaluation is necessary in the clinical setting.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.