ArticleMagnetic resonance in medicine2021
3D amplified MRI (aMRI).
Article in Magnetic resonance in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Magnetic resonance imaging of the pulsing brain: a systematic review.Magma (New York, N.Y.) · 2023Pooled it
- Effects and Correction of Patient Bulk Motion in Cranial DENSE MRI.Magnetic resonance in medicine · 2026Article
- Pulsatile Brain Motion as a Marker of Brain Aging and Dementia: Insights from 3D q-aMRI.medRxiv : the preprint server for health sciences · 2025Article
- A Novel Approach to Non-Invasive Intracranial Pressure Wave Monitoring: A Pilot Healthy Brain Study.Sensors (Basel, Switzerland) · 2025Article
- Evaluating amplified magnetic resonance imaging as an input for computational fluid dynamics models of the cerebrospinal fluid.Interface focus · 2025Article
- Exercise modulates brain pulsatility: insights from q-aMRI and MRI-based flow methods.Interface focus · 2025Article
- The pulsing brain: state of the art and an interdisciplinary perspective.Interface focus · 2025Review
- Dynamic visualization of brain pulsations using amplified MRI: methodology and applications.Interface focus · 2025Article
- Cerebrospinal fluid flow within ventricles and subarachnoid space evaluated by velocity selective spin labeling MRI.NeuroImage · 2025Article
- Phase stabilization with motion compensated diffusion weighted imaging.Magnetic resonance in medicine · 2024Article
- 3D Quantitative-Amplified Magnetic Resonance Imaging (3D q-aMRI).Bioengineering (Basel, Switzerland) · 2024Article
- MRI-based quantification of cardiac-driven brain biomechanics for early detection of neurological disorders.bioRxiv : the preprint server for biology · 2024Article
- A computational fluid dynamics study to assess the impact of coughing on cerebrospinal fluid dynamics in Chiari type 1 malformation.Scientific reports · 2024Article
- Single neurons in the thalamus and subthalamic nucleus process cardiac and respiratory signals in humans.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- DTI-MR fingerprinting for rapid high-resolution whole-brain TMagnetic resonance in medicine · 2024Article
- Neuraxial biomechanics, fluid dynamics, and myodural regulation: rethinking management of hypermobility and CNS disorders.Frontiers in neurology · 2024Review
- Updated Perspectives on the Neurobiology of Substance Use Disorders Using Neuroimaging.Substance abuse and rehabilitation · 2023Review
- Roadmap for an imaging and modelling paediatric study in rural NZ.Frontiers in physiology · 2023Article
- Motion robust magnetic resonance imaging via efficient Fourier aggregation.Medical image analysis · 2023Article
- Assessing pulsatile waveforms of paravascular cerebrospinal fluid dynamics within the glymphatic pathways using dynamic diffusion-weighted imaging (dDWI)NeuroImage · 2022Article
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Authors and funding
10 authors.
Funding
Abstract
purposeAmplified MRI (aMRI) has been introduced as a new method of detecting and visualizing pulsatile brain motion in 2D. Here, we improve aMRI by introducing a novel 3D aMRI approach.
methods3D aMRI was developed and tested for its ability to amplify sub-voxel motion in all three directions. In addition, 3D aMRI was qualitatively compared to 2D aMRI on multi-slice and 3D (volumetric) balanced steady-state free precession cine data and phase contrast (PC-MRI) acquired on healthy volunteers at 3T. Optical flow maps and 4D animations were produced from volumetric 3D aMRI data.
results3D aMRI exhibits better image quality and fewer motion artifacts compared to 2D aMRI. The tissue motion was seen to match that of PC-MRI, with the predominant brain tissue displacement occurring in the cranial-caudal direction. Optical flow maps capture the brain tissue motion and display the physical change in shape of the ventricles by the relative movement of the surrounding tissues. The 4D animations show the complete brain tissue and cerebrospinal fluid (CSF) motion, helping to highlight the "piston-like" motion of the ventricles.
conclusionsHere, we introduce a novel 3D aMRI approach that enables one to visualize amplified cardiac- and CSF-induced brain motion in striking detail. 3D aMRI captures brain motion with better image quality than 2D aMRI and supports a larger amplification factor. The optical flow maps and 4D animations of 3D aMRI may open up exciting applications for neurological diseases that affect the biomechanics of the brain and brain fluids.
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