ArticleThe journal of nutrition, health & aging2021
Hopelessness and Depression Predict Sarcopenia in Advanced CKD and Dialysis: A Multicenter Cohort Study.
Article in The journal of nutrition, health & aging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 44 citations in OpenAlex.
- The influence of mindfulness meditation combined with progressive muscle relaxation training on the clinical efficacy and quality of life of patients with sarcopenia receiving haemodialysis: a randomised controlled trial.BMC complementary medicine and therapies · 2024Trial
- Association of Posttransplant Kidney Function With Patient Reported Outcomes: A Single Center's Experience Over Nearly Two Decades.Clinical transplantation · 2026Article
- The association between nutritional status, sarcopenia, and depressive symptoms in elderly Chinese patients receiving maintenance hemodialysis: a hospital-based cross-sectional study.Frontiers in nutrition · 2026Article
- Sarcopenia and dynapenia are associated with depression rather than anxiety in Chinese hemodialysis patients.BMC psychiatry · 2025Article
- Possible sarcopenia and associated factors in community-dwelling older adults with a history of falls in the Republic of Korea: a cross-sectional study.BMC geriatrics · 2025Article
- Longitudinal Trajectories of Cognitive Function Among Chinese Middle-Aged and Older Adults: The Role of Sarcopenia and Depressive Symptoms.Brain sciences · 2025Article
- Dose-dependent association between estimated glomerular filtration rate and the subsequent risk of depression: An analysis of a nationwide epidemiological dataset.European journal of clinical investigation · 2025Article
- Integrative approaches to depression in end-stage renal disease: insights into mechanisms, impacts, and pharmacological strategies.Frontiers in pharmacology · 2025Review
- Association between health-related hope and distress from restrictions in chronic kidney disease and dialysis.BMC nephrology · 2024Observational
- Causality between Sarcopenia and Depression: A Bidirectional Mendelian Randomization Study.Actas espanolas de psiquiatria · 2024Article
- Prevention of Chronic Kidney Disease and Its Complications in Older Adults.Drugs & aging · 2024Review
- Analysis of Risk Factors of Sarcopenia in Patients with Maintenance Hemodialysis and Its Correlation with Emotional Status and Quality of Life.Journal of multidisciplinary healthcare · 2024Article
- Independent and joint influence of depression and advanced lung cancer inflammation index on mortality among individuals with chronic kidney disease.Frontiers in nutrition · 2024Article
- Comment on "Diagnosis, prevalence, and mortality of sarcopenia in dialysis patients: a systematic review and meta-analysis" by Shu et al.Journal of cachexia, sarcopenia and muscle · 2023Article
- Article
- Decreased Intracellular to Total Body Water Ratio and Depressive Symptoms in Patients with Maintenance Hemodialysis.Psychology research and behavior management · 2023Article
- "Alive Day is the Day": A Qualitative Study of Experiences of Learned Helplessness in Maintenance Haemodialysis Patients.Risk management and healthcare policy · 2023Article
- Depression and risk of sarcopenia: a national cohort and Mendelian randomization study.Frontiers in psychiatry · 2023Article
- The association between sense of coherence and quality of life: a cross-sectional study in a sample of patients on hemodialysis.BMC psychology · 2022Article
- Daytime napping, comorbidity profiles, and the risk of sarcopenia in older individuals.Frontiers in physiology · 2022Article
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
objectivesDepression and hopelessness are frequently experienced in chronic kidney disease (CKD) and are generally associated with lessened physical activity. The aim of this study was to quantify the associations between sarcopenia as determined by SARC-F with both depression and hopelessness. DESIGN AND
settingThis multicenter cohort study involving cross-sectional and longitudinal analyses was conducted in a university hospital and four general hospitals, each with a nephrology center, in Japan.
participantsParticipants consisted of 314 CKD patients (mean age 67.6), some of whom were receiving dialysis (228, 73%). MEASUREMENTS: The main exposures were depression, measured using the Center for Epidemiologic Studies Depression (CES-D) questionnaire, and hopelessness, measured using a recently developed 18-item health-related hope scale (HR-Hope). The outcomes were sarcopenia at baseline and one year after, measured using the SARC-F questionnaire. Logistic regression models were applied.
resultsThe cross-sectional and longitudinal analyses included 314 and 180 patients, respectively. Eighty-nine (28.3%) patients experienced sarcopenia at baseline, and 44 (24.4%) had sarcopenia at the one-year follow-up. More hopelessness (per 10-point lower, adjusted odds ratio [AOR]: 1.33, 95% confidence interval [95% CI] 1.12-1.58), depression (AOR: 1.87, 95% CI 1.003-3.49), age (per 10-year higher, AOR: 1.70, 95% CI 1.29-2.25), being female (AOR: 2.67, 95% CI 1.43-4.98), and undergoing hemodialysis (AOR, 2.92; 95% CI, 1.41-6.05) were associated with a higher likelihood of having baseline sarcopenia. More hopelessness (per 10-point lower, AOR: 1.69, 95% CI 1.14-2.51) and depression (AOR: 4.64, 95% CI: 1.33-16.2) were associated with a higher likelihood of having sarcopenia after one year.
conclusionsAmong patients with different stages of CKD, both hopelessness and depression predicted sarcopenia. Provision of antidepressant therapies or goal-oriented educational programs to alleviate depression or hopelessness can be useful options to prevent sarcopenia.
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