Evidence map›Paper›PMID 33949142›Full record

ArticleVeterinary medicine and science2021

Comparative study of antimicrobial action of aloe vera and antibiotics against different bacterial isolates from skin infection.

Safia Arbab, Hanif Ullah, Wang Weiwei, Xiaojuan Wei, Salah Uddin Ahmad, Lingyu Wu, Jiyu Zhang

Open access · goldAbstract read
In one paragraph

Article in Veterinary medicine and science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
7.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 63 citations in OpenAlex.

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  17. Evaluation of Antimicrobial Activity ofBioMed research international · 2025
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  19. The Effect ofMicroorganisms · 2024
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Safia ArbabKey Laboratory of Veterinary Pharmaceutical Development, Ministry of Agriculture, Lanzhou, China.ORCID 0000-0002-9940-9708
Hanif UllahKey Laboratory of New Animal Drug Project of Gansu Province, Lanzhou, China.
Wang WeiweiKey Laboratory of Veterinary Pharmaceutical Development, Ministry of Agriculture, Lanzhou, China.
Xiaojuan WeiKey Laboratory of Veterinary Pharmaceutical Development, Ministry of Agriculture, Lanzhou, China.
Salah Uddin AhmadKey Laboratory of Veterinary Pharmaceutical Development, Ministry of Agriculture, Lanzhou, China.
Lingyu WuKey Laboratory of Veterinary Pharmaceutical Development, Ministry of Agriculture, Lanzhou, China.
Jiyu ZhangKey Laboratory of Veterinary Pharmaceutical Development, Ministry of Agriculture, Lanzhou, China.
Lanzhou Institute of Husbandry and Pharmaceutical Sciences · CNShanghai Veterinary Research Institute · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aloe vera is reputed to have medicinal properties. For centuries, it has been used for an array of ailments such as mild fever, wounds and burns, gastrointestinal disorders, diabetes, sexual vitality and fertility problems to cancer, immune modulation, AIDS and various skin infections. In present study, antibacterial activity of aloe vera gel extracts was tested against some common skin infection pathogens, that is, Escherichia coli, Shigella, Salmonella spp. and Staphylococcus aureus all were recorded positive. Antibiotic resistance and susceptibility pattern of above isolates were also studied against 10 clinically significant antibiotics (ampicillin [AMC], amoxicillin, augmentin, cefotaxime, ceftazidime [CAZ], cefuroxime [CXM], ciprofloxaci, tetracycline, cefpodoxime and imipenem). AMC and CXM were found to be most effective antibiotic followed by CXM with highest efficacy against Gram-negative bacteria. In case of CAZ showed highest efficacy was showed against Gram-positive bacteria. Aloe vera leave gel was extracted with four different solvent-like aloe vera leaf extract, root extract, leaf ethanol extract and root ethanol extract; however, Gram-negative as well Gram-positive isolates was found highest susceptibility with aloe leaf and aloe root ethanol extract. Moderate sensitivity observed with aloe leaf extract and aloe root extract against both Gram-positive as well as Gram-negative bacterial isolates. This result showed that ethanol extracts of aloe vera both leaf and root can be used alongside conventional antibiotics to fight agents of infections that are so prevalent in the skin infection.

Indexed as

AloeAnti-Bacterial AgentsPlant ExtractsAnimalsEscherichia coliGram-Negative BacteriaGram-Positive BacteriaSkin Diseases, BacterialStaphylococcal InfectionsAnti-Bacterial AgentsPlant Extractsaloe veraantibacterialextractskin infectionzone inhibition

Identifiers

PMID33949142
PMCPMC8464272
OpenAlexW3159368857

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.