ArticleActa ophthalmologica2022
Optic disc morphology and peripapillary atrophic changes in diabetic children and adults without diabetic retinopathy or visual impairment.
Article in Acta ophthalmologica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 23 citations in OpenAlex.
- Optic disc morphology and myopia severity in eyes with peripapillary hyperreflective ovoid mass-like structures.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Morphological changes of β-Zone Peripapillary Atrophy (β-PPA) in children with type 1 Diabetes: A longitudinal study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Observational
- Three-Dimensional Reconstruction for Localizing Retinal Tears in Treatment of Rhegmatogenous Retinal Detachment by Foldable Capsular Buckle.Clinical ophthalmology (Auckland, N.Z.) · 2026Article
- Photoreceptor Layer Thinning as Biomarker for Circulatory Premature Mortality: UK Biobank Cohort Study.Translational vision science & technology · 2025Article
- Short-Chain Fatty Acids Are Potential Biomarkers of Immune Regulation in Diabetic Retinopathy.Investigative ophthalmology & visual science · 2025Article
- Gut microbiota predict retinopathy in patients with diabetes: A longitudinal cohort study.Applied microbiology and biotechnology · 2024Article
- Optic disc characteristics on digital fundus photographs in Saudi children.Neurosciences (Riyadh, Saudi Arabia) · 2024Article
- Remnant cholesterol is correlated with retinal vascular morphology and diabetic retinopathy in type 2 diabetes mellitus: a cross-sectional study.Lipids in health and disease · 2024Article
- The retinal ganglion cells in metabolic syndrome.Annals of translational medicine · 2024Article
- The protective role of gamma zone peripapillary atrophy in diabetic retinopathy: insights from deep learning and SS-OCT angiography.Frontiers in cell and developmental biology · 2024Article
- Unveiling the hidden: a deep learning approach to unraveling subzone-specific changes in peripapillary atrophy in type 2 diabetes.Frontiers in cell and developmental biology · 2024Article
- Changes and related factors of blood CCN1 levels in diabetic patients.Frontiers in endocrinology · 2023Article
- Increased serum 12-hydroxyeicosatetraenoic acid levels are correlated with an increased risk of diabetic retinopathy in both children and adults with diabetes.Acta diabetologica · 2022Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
purposeTo investigate the changes in optic disc morphology and peripapillary atrophy (PPA) in diabetic children and adults without diabetic retinopathy (DR) or visual impairment (VI).
methodsThis cross-sectional study included two groups of subjects. One group included 91 children with type 1 diabetes mellitus (T1DM) and 86 healthy children, and the other group included 444 adults with T2DM and 442 healthy controls. The optic disc parameters including major and minor axis lengths, optic disc ovality (ODO), optic disc tilt, optic disc area and β-PPA area were analysed in all subjects. Optic disc rotation and the Bergmeister papilla were analysed only in children. Patients with diabetes and healthy controls were compared in each group of the study population.
resultsIn both groups, patients with diabetes and healthy controls were matched for age, sex and axial length (AL). Among the children, β-PPA area was significantly smaller in those with diabetes (0.29 ± 0.43 mm
conclusionHyperglycaemia had different effects on the optic disc in children and adults. Unlike in healthy controls, hyperglycaemia had an impact on the peripapillary tissue in children and on optic disc shape in adults before DR and VI development.
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