ArticleSocial psychiatry and psychiatric epidemiology2021
First help-seeking attempt before and after psychosis onset: measures of delay and aversive pathways to care.
Article in Social psychiatry and psychiatric epidemiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- On the proportion of patients who experience a prodrome prior to psychosis onset: A systematic review and meta-analysis.Molecular psychiatry · 2024Pooled it
- Examining the Effectiveness of a Digital Media Campaign at Reducing the Duration of Untreated Psychosis in New York State: Results From a Stepped-wedge Randomized Controlled Trial.Schizophrenia bulletin · 2024Trial
- A comparison of pathways to care in at-risk mental states and first episode psychosis: a mental health electronic clinical records analysis in the East of England, UK.Social psychiatry and psychiatric epidemiology · 2025Article
- The impact of early detection (ED) campaigns on care presentations: Beyond DUP reduction.Schizophrenia research · 2024Article
- Sampling from different populations: Sociodemographic, clinical, and functional differences between samples of first episode psychosis individuals and clinical high-risk individuals who progressed to psychosis.Schizophrenia research · 2023Article
- Identification of Diagnostic Schizophrenia Biomarkers Based on the Assessment of Immune and Systemic Inflammation Parameters Using Machine Learning Modeling.Sovremennye tekhnologii v meditsine · 2023Article
- The Mini-SIPS: development of a brief clinical structured interview guide to diagnosing DSM-5 Attenuated Psychosis Syndrome and training outcomes.BMC psychiatry · 2022Article
- Machine Learning and Non-Affective Psychosis: Identification, Differential Diagnosis, and Treatment.Current psychiatry reports · 2022Review
- Changes in community providers' screening behaviours, referral practices, and clinical confidence following participation in an early psychosis educational campaign.Early intervention in psychiatry · 2022Article
- Early Intervention Services for Schizophrenia: Looking Back and Looking Ahead.Schizophrenia bulletin · 2022Article
- Timing of cannabis exposure relative to prodrome and psychosis onset in a community-based first episode psychosis sample.Journal of psychiatric research · 2022Article
- Granular analysis of pathways to care and durations of untreated psychosis: A marginal delay model.PloS one · 2022Article
- Reducing the Duration of Untreated Psychosis (DUP) in a US Community: A Quasi-Experimental Trial.Schizophrenia bulletin open · 2022Article
- Help-Seekers in an Early Detection of Psychosis Service: The Non-cases.Frontiers in psychiatry · 2021Article
- Quality evaluation of information about sudden sensorineural hearing loss on TikTok videos: Cross-sectional study.Digital healthArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
purposeDelay in receiving effective treatment for psychosis adversely impacts outcomes. We investigated the timing of the first help-seeking attempt in individuals with recent onset non-affective psychosis by comparing those who sought help during the prodrome to those who sought help after psychosis onset across sociodemographic and clinical characteristics, overall functioning, and occurrence of aversive events during their pathways to care.
methodsPatients were admitted from February 1st, 2014 to January 31st, 2019 to the Program for Specialized Treatment Early in Psychosis (STEP) in New Haven, CT. Psychosis-onset date was ascertained using the Structured Interview for Psychosis-risk Syndromes. Key dates before and after psychosis onset, along with initiators and aversive events, were collected via semi-structured interview.
resultsWithin 168 individuals, 82% had their first help-seeking episode after psychosis onset and did not differ in terms of sociodemographic characteristics from prodrome help seekers. When the first help-seeking episode started before (i.e., during prodrome) vs after psychosis onset it was mostly initiated by patients vs family members (Cramer's V = 0.23, p = 0.031) and led to a faster prescription of an antipsychotic once full-blown psychosis emerged (time to antipsychotic since psychosis onset = 21 vs 56 days, p = 0.03). No difference in aversive events before STEP enrollment was detected across groups.
conclusionHelp seeking during the prodrome is associated with faster initiation of antipsychotic treatment and is more likely to be self-initiated, compared to help seeking after psychosis onset. Early detection efforts that target prodromal samples may improve the length and experience of pathways to care.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.