Evidence map›Paper›PMID 33948532›Full record

ArticleCurrent developments in nutrition2021

The Impact of Double-Fortified Salt Delivered Through the Public Distribution System on Iodine Status in Women of Reproductive Age in Rural India.

Ujwala Godbole, Mahesh Basantani, Subhash Yadav, Nachiket Godbole, Sukhanshi Khandpur, Madan Godbole, Sana Raza, Mduduzi N N Mbuya, Lynnette M Neufeld

Open access · goldAbstract read
In one paragraph

Article in Current developments in nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. India's tryst with salt: Dandi march to low sodium salts.The Indian journal of medical research · 2023
    Review
  3. Field-friendly MUNNGFrontiers in nutrition · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Ujwala GodboleInstitute of Bioscience and Technology, Shri Ramswaroop Memorial University, Barabanki, Uttar Pradesh, India.
Mahesh BasantaniInstitute of Bioscience and Technology, Shri Ramswaroop Memorial University, Barabanki, Uttar Pradesh, India.
Subhash YadavDepartment of Endocrinology, Molecular Medicine, and Biotechnology, UP-USI Coalition, Sanjay Gandhi Postgraduate Institute campus, Lucknow, India.
Nachiket GodboleDepartment of Endocrinology, Molecular Medicine, and Biotechnology, UP-USI Coalition, Sanjay Gandhi Postgraduate Institute campus, Lucknow, India.
Sukhanshi KhandpurDepartment of Endocrinology, Molecular Medicine, and Biotechnology, UP-USI Coalition, Sanjay Gandhi Postgraduate Institute campus, Lucknow, India.
Madan GodboleDepartment of Endocrinology, Molecular Medicine, and Biotechnology, UP-USI Coalition, Sanjay Gandhi Postgraduate Institute campus, Lucknow, India.ORCID https://orcid.org/0000-0001-9604-8284
Sana RazaDepartment of Endocrinology, Molecular Medicine, and Biotechnology, UP-USI Coalition, Sanjay Gandhi Postgraduate Institute campus, Lucknow, India.
Mduduzi N N MbuyaGlobal Alliance for Improved Nutrition, Washington, DC, USA.ORCID https://orcid.org/0000-0003-1230-2367
Lynnette M NeufeldGlobal Alliance for Improved Nutrition, Geneva, Switzerland.ORCID https://orcid.org/0000-0003-2652-9108
Sanjay Gandhi Post Graduate Institute of Medical Sciences · INShri Ramswaroop Memorial University · INAmerican Society for Nutrition · USGlobal Alliance for Improved Nutrition · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDouble-fortified salt (DFS) with iron and iodine has been demonstrated to be efficacious but questions of unintended effects on the gains in salt iodization remain. The main cross-sectional study based on the use of DFS over 1 y showed a reduction in iron deficiency risk. Whether the programs and the levels of added iron can adversely affect iodine status is yet to be established.

objectivesWe hypothesized that the addition of iron to iodized salt can adversely affect iodine status in women of reproductive age (WRA).

methodsA cross-sectional substudy was conducted in 4 matched-pair adjacent districts of rural Uttar Pradesh, India, in 2019. Under the public distribution system (PDS), DFS was available for 1 y through Fair Price Shops, in the 2 DFS supply districts (DFS-SDs). In these districts, iodized salt was also available in the market. In the 2 compared DFS nonsupply districts (DFS-NSDs), only iodized salt was available. In the substudy, participants included WRA (

resultsSignificantly fewer women from the DFS-SDs had median urinary iodine concentration values indicative of moderate to mild iodine deficiency compared with the women from the DFS-NSDs. The salt purchase pattern and iodine content revealed that significantly fewer (21.99%) households in the DFS-SDs were purchasing inadequately iodized crystal salt, compared with 36.04% households in the DFS-NSDs.

conclusionsThe data reject the working hypothesis and suggest a beneficial effect of the DFS program on the iodine status in WRA, thereby supporting a recommendation of DFS supply through the PDS.

Indexed as

double fortified saltiodized saltsalt iodine contenturinary iodine concentrationwomen of reproductive age

Identifiers

PMID33948532
PMCPMC8075773
OpenAlexW3148665498

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.