ArticleInternational journal of cardiology. Heart & vasculature2021
Rhythm monitoring strategies for atrial fibrillation detection in patients with cryptogenic stroke: A systematic review and meta-analysis.
Article in International journal of cardiology. Heart & vasculature, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- Effect of implantable cardiac monitors on preventing stroke: A systematic review and meta-analysis of randomized clinical trials.PloS one · 2023Pooled it
- A meta-analysis of extended ECG monitoring in detection of atrial fibrillation in patients with cryptogenic stroke.Open heart · 2022Pooled it
- Integration of transcriptome and mendelian randomization analyses to explore the molecular mechanisms of atrial fibrillation.Journal of cardiothoracic surgery · 2026Article
- Article
- An efficient approach for detecting atrial fibrillation in ischemic stroke patients using a wearable device: a prospective multicenter substudy of the STABLED trial.Frontiers in neurology · 2025Article
- Atrial Imaging and Cardiac Rhythm in Cryptogenic Embolic Stroke: The ARIES Study.Journal of the American Heart Association · 2024Observational
- A Patient-Centered Approach to Cardiac Monitoring After Cryptogenic Stroke: A Review.Stroke (Hoboken, N.J.) · 2024Review
- Left atrial appendage flow velocity predicts occult atrial fibrillation in cryptogenic stroke: a CRYPTON-ICM registry.Journal of neurology · 2023Article
- Recent Advances in Antiarrhythmic Drug Therapy.Drugs · 2023Review
- Recent highlights on the mechanistic basis of cardiovascular remodeling from theInternational journal of cardiology. Heart & vasculature · 2023Article
- ECG Smart Monitoring versus Implantable Loop Recorders for Atrial Fibrillation Detection after Cryptogenic Stroke-An Overview for Decision Making.Journal of cardiovascular development and disease · 2023Review
- Frequent premature atrial contractions as a signalling marker of atrial cardiomyopathy, incident atrial fibrillation, and stroke.Cardiovascular research · 2023Article
- Patent Foramen Ovale and Cryptogenic Stroke: Integrated Management.Journal of clinical medicine · 2023Review
- Advances in Neurological Diseases and Stroke.Journal of cardiovascular development and disease · 2023Article
- Atrial fibrillation detection using insertable cardiac monitor after stroke: A real-world cohort study.Journal of cardiovascular electrophysiology · 2023Article
- Clinical Implications of Atrial Fibrillation Detection Using Wearable Devices in Patients With Cryptogenic Stroke (CANDLE-AF) Trial: Design and Rationale.Frontiers in cardiovascular medicine · 2022Article
- Automated risk assessment of newly detected atrial fibrillation poststroke from electronic health record data using machine learning and natural language processing.Frontiers in cardiovascular medicine · 2022Article
- Non-stenotic Carotid Plaques in Embolic Stroke of Unknown Source.Frontiers in neurology · 2021Review
- Long-Term Cardiac Rhythm Monitoring After Ischemic Stroke: Detecting Atrial Fibrillation in the Era of Atrial Cardiopathy.Missouri medicineReview
Corrections and comments
- Commented on by
Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo summarize data on atrial fibrillation (AF) detection rates and predictors across different rhythm monitoring strategies in patients with cryptogenic stroke (CS) or embolic stroke of undetermined source (ESUS).
methodsMEDLINE, Embase, and Web of Science were searched to identify all published studies providing relevant data through July 6, 2020. Random-effects meta-analysis method was used to pool estimates.
resultsWe included 47 studies reporting on a pooled population of 8,215 patients with CS or ESUS. Using implantable cardiac monitor (ICM), the pooled rate of AF was 12.2% (95% CI 9.4-15.0) at 3 months, 16.0% (95% CI 13.2-18.8) at 6 months, 18.7% (95% CI 15.7-21.7) at 12 months, 22.8% (95% CI 19.1-26.5) at 24 months, and 28.5% (95% CI 17.6-39.3) at 36 months. AF rates were significantly higher in patients with ESUS vs CS (22.0% vs 14.2%;
conclusionThe yield of ICM increases with the duration of monitoring. More than a quarter of patients with CS or ESUS will be diagnosed with AF during follow-up. About one in seven patients had AF detected within a month of MCOT, suggesting that a non-invasive rhythm monitoring strategy should be considered before invasive monitoring.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.