Evidence map›Paper›PMID 33948393›Full record

ArticleIEEE journal of translational engineering in health and medicine2021

Clinically Applicable Machine Learning Approaches to Identify Attributes of Chronic Kidney Disease (CKD) for Use in Low-Cost Diagnostic Screening.

Md Rashed-Al-Mahfuz, Abedul Haque, Akm Azad, Salem A Alyami, Julian M W Quinn, Mohammad Ali Moni

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Article in IEEE journal of translational engineering in health and medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  11. To predict the risk of chronic kidney disease (CKD) using Generalized Additive2 Models (GA2M).Journal of the American Medical Informatics Association : JAMIA · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Md Rashed-Al-MahfuzDepartment of Computer Science and EngineeringUniversity of RajshahiRajshahi6205Bangladesh.
Abedul HaqueDepartment of HematopathologyThe University of Texas MD Anderson Cancer CenterHoustonTX77030USA.
Akm AzadiThree Institute, University of Technology SydneyNSW2007Australia.
Salem A AlyamiDepartment of Mathematics and StatisticsImam Muhammad Ibn Saud Islamic UniversityRiyadh13318Saudi Arabia.
Julian M W QuinnBone Biology DivisionGarvan Institute of Medical ResearchDarlinghurstNSW2010Australia.
Mohammad Ali MoniWHO Collaborating Centre of eHealth, School of Public Health and Community MedicineUniversity of New South WalesSydneyNSW2052Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveChronic kidney disease (CKD) is a major public health concern worldwide. High costs of late-stage diagnosis and insufficient testing facilities can contribute to high morbidity and mortality rates in CKD patients, particularly in less developed countries. Thus, early diagnosis aided by vital parameter analytics using affordable computer-aided diagnosis could not only reduce diagnosis costs but improve patient management and outcomes.

methodsIn this study, we developed machine learning models using selective key pathological categories to identify clinical test attributes that will aid in accurate early diagnosis of CKD. Such an approach will save time and costs for diagnostic screening. We have also evaluated the performance of several classifiers with k-fold cross-validation on optimized datasets derived using these selected clinical test attributes.

resultsOur results suggest that the optimized datasets with important attributes perform well in diagnosis of CKD using our proposed machine learning models. Furthermore, we evaluated clinical test attributes based on urine and blood tests along with clinical parameters that have low costs of acquisition. The predictive models with the optimized and pathologically categorized attributes set yielded high levels of CKD diagnosis accuracy with random forest (RF) classifier being the best performing.

conclusionsOur machine learning approach has yielded effective predictive analytics for CKD screening which can be developed as a resource to facilitate improved CKD screening for enhanced and timely treatment plans.

Indexed as

Machine LearningRenal Insufficiency, ChronicDiagnosis, Computer-AssistedEarly DiagnosisHumansAttribute selectionchronic kidney disease (CKD)computer-aided diagnosisexplainable AImachine learning (ML)

Identifiers

PMID33948393
PMCPMC8075287

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.