Evidence map›Paper›PMID 33948277›Full record

ArticleJournal of clinical and translational science2020

A novel system to collect dual pulse oximetry data for critical congenital heart disease screening research.

Kavish Doshi, Gregory B Rehm, Pranjali Vadlaputi, Zhengfeng Lai, Satyan Lakshminrusimha, Chen-Nee Chuah, Heather M Siefkes

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical and translational science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. A Machine Learning Driven Pipeline for Automated Photoplethysmogram Signal Artifact Detection....IEEE...International Conference on Connected Health: Applications, Systems and Engineering Technologies. IEEE International Conference on Connected Health: Applications, Systems and Engineering Technologies · 2021
    Article
  3. Enhanced Critical Congenital Cardiac Disease Screening by Combining Interpretable Machine Learning Algorithms.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Kavish DoshiDepartment of Computer Science, University of California, Davis, Davis, CA, USA.
Gregory B RehmDepartment of Computer Science, University of California, Davis, Davis, CA, USA.
Pranjali VadlaputiDepartment of Pediatrics, University of California, Davis, Sacramento, CA, USA.
Zhengfeng LaiDepartment of Electrical and Computer Engineering, University of California, Davis, Davis, CA, USA.
Satyan LakshminrusimhaDepartment of Pediatrics, University of California, Davis, Sacramento, CA, USA.
Chen-Nee ChuahDepartment of Electrical and Computer Engineering, University of California, Davis, Davis, CA, USA.
Heather M SiefkesDepartment of Pediatrics, University of California, Davis, Sacramento, CA, USA.
University of California, Davis · US

Funding

UC Davis Clinical and Translational Science CenterUL1TR001860 · NCATS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KENYON, NICHOLAS J., LYLES, COURTNEY REES · 2016 to 2025
$47.3M
Institutional Career Development Core (KL2)KL2TR001859 · NCATS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI HOLMES, JAMES F. · 2016 to 2025
$10.1M
Improving Critical Congenital Heart Disease Screening and Detection of "Secondary" TargetsR21HD099239 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI SIEFKES, HEATHER M · 2019 to 2020
$433k
NCATS NIH HHS KL2 TR001859NCATS NIH HHS UL1 TR001860NICHD NIH HHS R21 HD099239
6 · The paper itself

Abstract

introductionAccess to patient medical data is critical to building a real-time data analytic pipeline for improving care providers' ability to detect, diagnose, and prognosticate diseases. Critical congenital heart disease (CCHD) is a common group of neonatal life-threatening defects that must be promptly diagnosed to minimize morbidity and mortality. CCHD can be diagnosed both prenatally and postnatally. However, despite current screening practices involving oxygen saturation analysis, timely diagnosis is missed in approximately 900 infants with CCHD annually in the USA and can benefit from increased data processing capabilities. Adding non-invasive perfusion measurements to oxygen saturation data can improve the timeliness and fidelity of CCHD diagnostics. However, real-time monitoring and interpretation of non-invasive perfusion data are currently limited.

methodsTo address this challenge, we created a hardware and software architecture utilizing a Pi-top™ for collecting, visualizing, and storing dual oxygen saturation, perfusion indices, and photoplethysmography data. Data aggregation in our system is automated and all data files are coded with unique study identifiers to facilitate research purposes.

resultsUsing this system, we have collected data from 190 neonates, 130 presumably without and 60 with congenital heart disease, in total comprising 1665 min of information. From these data, we are able to extract non-invasive perfusion features such as perfusion index, radiofemoral delay, and slope of systolic rise or diastolic fall.

conclusionThis data collection and waveform analysis is relatively inexpensive and can be used to enhance future CCHD screening algorithms.

Indexed as

Congenital heart disease screeningpulse oximetry

Identifiers

PMID33948277
PMCPMC8057385
OpenAlexW3093711640

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.