ReviewNature reviews. Genetics2021
Testing at scale during the COVID-19 pandemic.
Review in Nature reviews. Genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06047067 (BIOAEROSOL SAMPLING DEVICE), which is not on this map. Cited by 213 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
BIOAEROSOL SAMPLING DEVICE (BSD) CLINICAL STUDY: Performance of Respiratory Pathogen Bioaerosol Sampling Device Compared to Matched Swab Sample With Molecular and Antigen Assays That Can Detect SARS-CoV-2 Phase II Validation
Who cites it
213 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Effectiveness of testing, contact tracing and isolation interventions among the general population on reducing transmission of SARS-CoV-2: a systematic review.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2023Pooled it
- Influence of seasonal and operator variations on diagnostic accuracy of lateral flow devices during the COVID-19 pandemic: a systematic review and meta-analysis.Clinical medicine (London, England) · 2023Pooled it
- Diagnostic Accuracy of SARS-CoV-2 Antigen Tests for Community Transmission Screening: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2021Pooled it
- Population-Based Digital Health Interventions to Deliver at-Home COVID-19 Testing: SCALE-UP II Randomized Clinical Trial.Journal of medical Internet research · 2025Trial
- Feasibility of wearable sensor signals and self-reported symptoms to prompt at-home testing for acute respiratory viruses in the USA (DETECT-AHEAD): a decentralised, randomised controlled trial.The Lancet. Digital health · 2024Trial
- Cost and cost-effectiveness of four different SARS-CoV-2 active surveillance strategies: evidence from a randomised control trial in Germany.The European journal of health economics : HEPAC : health economics in prevention and care · 2023Trial
- Comparison of Four Active SARS-CoV-2 Surveillance Strategies in Representative Population Sample Points: Two-Factor Factorial Randomized Controlled Trial.JMIR public health and surveillance · 2023Trial
- Variations in the Risk of New-Onset Diabetes Following COVID-19 Infection Across Body Mass Index, Deprivation, Ethnicity and Geographic Regions: Population-Based Cohort Study in 42 Million People in England.Diabetes, obesity & metabolism · 2026Article
- Viral Infection-Inspired Autonomous Detection of Fusion-Competent Viruses for Screening and Environmental Surveillance.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- CV19global: harmonized epidemiology, policy, mobility and weather indicators from two years and 54 countries.Scientific data · 2026Article
- Simultaneous detection of SARS-CoV-2 proteins and nucleic acids by coupling PNIPAM with circle-to-circle amplification.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2026Article
- Lessons Learned: Defining the Right Specifications for Diagnostics in Outbreak Situations.Infectious diseases and therapy · 2026Article
- Site-specific wastewater-based surveillance in early detection of COVID-19 new cases and prediction of mass testing outcomes in long-term care facilities.Scientific reports · 2026Article
- Remotely Controlled Continuous Surveillance of Viral RNA in Wastewater Using a LoRa Network.IEEE internet of things journal · 2026Article
- Enhancing COVID-19 Screening Models With Epidemiological and Mobility Features: Machine-Learning Model Study.JMIR AI · 2026Article
- Adherence to mask wearing and social distancing and use of lateral flow tests during the COVID19 pandemic in England and Wales based on the virus watch community cohort study.Discover public health · 2026Article
- Integrating isothermal amplification with magnetic flocculation and DNA-guided PfAgo for SARS-CoV-2 detection.Frontiers in microbiology · 2026Article
- Demand creation for testing and Covid-19 surveillance indicators in the Covid-19 Testing, Isolation, Quarantine, and Telemonitoring Study.Revista de saude publica · 2026Article
- Integration of COVID-19 testing into existing ILI surveillance system in Ghana.PLOS global public health · 2026Article
- SARS-CoV-2 testing behavior in symptomatic adults in a U.S. national cohort, 2020-2023: influence of exposure risk, susceptibility and healthcare access.BMC public health · 2025Article
153 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Assembly and publication of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome in January 2020 enabled the immediate development of tests to detect the new virus. This began the largest global testing programme in history, in which hundreds of millions of individuals have been tested to date. The unprecedented scale of testing has driven innovation in the strategies, technologies and concepts that govern testing in public health. This Review describes the changing role of testing during the COVID-19 pandemic, including the use of genomic surveillance to track SARS-CoV-2 transmission around the world, the use of contact tracing to contain disease outbreaks and testing for the presence of the virus circulating in the environment. Despite these efforts, widespread community transmission has become entrenched in many countries and has required the testing of populations to identify and isolate infected individuals, many of whom are asymptomatic. The diagnostic and epidemiological principles that underpin such population-scale testing are also considered, as are the high-throughput and point-of-care technologies that make testing feasible on a massive scale.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.