Evidence map›Paper›PMID 33947917›Full record

ArticleScientific reports2021

2-step deep learning model for landmarks localization in spine radiographs.

Andrea Cina, Tito Bassani, Matteo Panico, Andrea Luca, Youssef Masharawi, Marco Brayda-Bruno, Fabio Galbusera

Abstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Spinopelvic measurements of sagittal balance with deep learning: systematic review and critical evaluation.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2022
    Pooled it
  2. Article
  3. Automatic detection of spinal pathologies based on MRI scans.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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  17. Performance evaluation of a deep learning-based cascaded HRNet model for automatic measurement of X-ray imaging parameters of lumbar sagittal curvature.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024
    Article
  18. Estimating lumbar bone mineral density from conventional MRI and radiographs with deep learning in spine patients.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Andrea CinaIRCCS Istituto Ortopedico Galeazzi, Via Riccardo Galeazzi 4, 20161, Milan, Italy. andrea.cina@grupposandonato.it.
Tito BassaniIRCCS Istituto Ortopedico Galeazzi, Via Riccardo Galeazzi 4, 20161, Milan, Italy.
Matteo PanicoIRCCS Istituto Ortopedico Galeazzi, Via Riccardo Galeazzi 4, 20161, Milan, Italy.
Andrea LucaDepartment of Spine Surgery III, IRCCS Istituto Ortopedico Galeazzi, Via Riccardo Galeazzi 4, 20161, Milan, Italy.
Youssef MasharawiDepartment of Physiotherapy, Sackler Faculty of Medicine, The Stanley Steyer School of Health Professions, Tel Aviv University, Tel Aviv, Israel.
Marco Brayda-BrunoDepartment of Spine Surgery III, IRCCS Istituto Ortopedico Galeazzi, Via Riccardo Galeazzi 4, 20161, Milan, Italy.
Fabio GalbuseraIRCCS Istituto Ortopedico Galeazzi, Via Riccardo Galeazzi 4, 20161, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this work we propose to use Deep Learning to automatically calculate the coordinates of the vertebral corners in sagittal x-rays images of the thoracolumbar spine and, from those landmarks, to calculate relevant radiological parameters such as L1-L5 and L1-S1 lordosis and sacral slope. For this purpose, we used 10,193 images annotated with the landmarks coordinates as the ground truth. We realized a model that consists of 2 steps. In step 1, we trained 2 Convolutional Neural Networks to identify each vertebra in the image and calculate the landmarks coordinates respectively. In step 2, we refined the localization using cropped images of a single vertebra as input to another convolutional neural network and we used geometrical transformations to map the corners to the original image. For the localization tasks, we used a differentiable spatial to numerical transform (DSNT) as the top layer. We evaluated the model both qualitatively and quantitatively on a set of 195 test images. The median localization errors relative to the vertebrae dimensions were 1.98% and 1.68% for x and y coordinates respectively. All the predicted angles were highly correlated with the ground truth, despite non-negligible absolute median errors of 1.84°, 2.43° and 1.98° for L1-L5, L1-S1 and SS respectively. Our model is able to calculate with good accuracy the coordinates of the vertebral corners and has a large potential for improving the reliability and repeatability of measurements in clinical tasks.

Indexed as

Deep LearningHumansLordosisLumbar VertebraeNeural Networks, ComputerRadiographyReproducibility of ResultsSpine

Identifiers

PMID33947917
PMCPMC8096829

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.