Evidence map›Paper›PMID 33947712›Full record

ArticleBMJ open gastroenterology2021

Point-of-care faecal calprotectin testing in patients with paediatric inflammatory bowel disease during the COVID-19 pandemic.

Mwansa Jere, Vikki Garrick, Lee Curtis, Rachel Tayler, Lisa Gervais, Konstantinos Gerasimidis, Richard Hansen

Open access · goldAbstract read
In one paragraph

Article in BMJ open gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Mwansa JereDepartment of Paediatric Gastroenterology, Royal Hospital for Children, Glasgow, UK.ORCID 0000-0003-0497-3347
Vikki GarrickDepartment of Paediatric Gastroenterology, Royal Hospital for Children, Glasgow, UK.
Lee CurtisDepartment of Paediatric Gastroenterology, Royal Hospital for Children, Glasgow, UK.
Rachel TaylerDepartment of Paediatric Gastroenterology, Royal Hospital for Children, Glasgow, UK.
Lisa GervaisDepartment of Paediatric Gastroenterology, Royal Hospital for Children, Glasgow, UK.
Konstantinos GerasimidisDepartment of Human Nutrition, University of Glasgow, Glasgow, UK.
Richard HansenDepartment of Paediatric Gastroenterology, Royal Hospital for Children, Glasgow, UK richard.hansen@glasgow.ac.uk.ORCID 0000-0002-3944-6646
Royal Hospital for Children · GBUniversity of Glasgow · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesFollowing the disruption of normal paediatric inflammatory bowel disease (IBD) services during the peak of the COVID-19 pandemic, we prospectively audited the first-time use of home faecal calprotectin testing. We aimed to provide an alternative to laboratory tests and to assess the value of home testing as part of our regular services going forward.

methodsHome test kits as well as accompanying user instructions were made available to our patients with paediatric IBD that required faecal calprotectin test between 17 April and 12 August 2020. Once the user completed the test, results were automatically uploaded to the result portal and clinical staff were alerted. A user feedback questionnaire was sent to users that had completed the home test.

resultsOf the 54 patients, 41 (76%) aged between 4.7 and 18.1 years used the home test. A total of 45 home tests were done, one of which produced an invalid result. The decision to modify management was made in 12 (29%) of the patients, while 14 (34%) had no changes made and 15 (37%) required further assessment. Twenty (48.8%) responded to the questionnaire and 85% stated that they preferred the home test to the laboratory testing method.

conclusionsHome calprotectin tests were useful in guiding clinical management during a time when laboratory testing was less available. They may offer benefits as part of routine paediatric IBD monitoring to help target appointments and reduce unnecessary hospital attendances in the future.

Indexed as

PandemicsPoint-of-Care TestingAdolescentBiomarkersChildChild, PreschoolClinical Chemistry TestsCOVID-19FecesFeedbackFemaleHome Care ServicesHumansInflammatory Bowel DiseasesLeukocyte L1 Antigen ComplexMaleBiomarkersLeukocyte L1 Antigen ComplexReagent Kits, DiagnosticCrohn's diseaseinflammatory bowel diseasestool markersulcerative colitis

Identifiers

PMID33947712
PMCPMC8098232
OpenAlexW3159062264

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.