Evidence map›Paper›PMID 33947477›Full record

ArticleBorderline personality disorder and emotion dysregulation2021

Impaired mentalizing in depression and the effects of borderline personality disorder on this relationship.

R P Rifkin-Zybutz, P Moran, T Nolte, Janet Feigenbaum, Brooks King-Casas, London Personality and Mood Disorder Consortium, P Fonagy, R P Montague

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Borderline personality disorder and emotion dysregulation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

R P Rifkin-ZybutzCentre for Academic Mental Health, University of Bristol, Oakfield House, Bristol, BS8 2BN, UK. jb19343@bristol.ac.uk.ORCID http://orcid.org/0000-0003-1230-0847
P MoranCentre for Academic Mental Health, University of Bristol, Oakfield House, Bristol, BS8 2BN, UK.
T NolteWellcome Department of Imaging Neuroscience, University College London, London, UK.
Janet FeigenbaumAnna Freud National Centre for Children and Families, University College London, London, UK.
Brooks King-CasasCentre for Academic Mental Health, University of Bristol, Oakfield House, Bristol, BS8 2BN, UK.
London Personality and Mood Disorder Consortium
P FonagyAnna Freud National Centre for Children and Families, University College London, London, UK.
R P MontagueResearch Department of Clinical, Educational, and Health Psychology, University College London, London, UK.
Anna Freud Centre · GBUniversity of Bristol · GBJefferson College of Health Sciences · USUniversity College London · GB

Funding

Neurobehavioral Mechanisms of Social Dysfunction in Borderline Personality DisorderR01MH115221 · NIMH · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI CASAS, BROOKS · 2018 to 2022
$3.3M
NIMH NIH HHS R01 MH115221
6 · The paper itself

Abstract

backgroundMentalizing, the ability to understand the self and others as well as behaviour in terms of intentional mental states, is impaired in Borderline Personality Disorder (BPD). Evidence for mentalizing deficits in other mental disorders, such as depression, is less robust and these links have never been explored while accounting for the effects of BPD on mentalizing. Additionally, it is unknown whether BPD symptoms might moderate any relationship between depressive symptoms and mentalizing.

methodsUsing multivariate regression modelling on cross-sectional data obtained from a sample of 274 participants recruited from clinical settings, we investigated the association between mentalizing impairment and depression and examined whether this was moderated by the presence and number of concurrent BPD symptoms, while adjusting for socio-demographic confounders.

resultsImpaired mentalizing was associated with depressive symptoms, after adjustment for socio-demographic confounders and BPD symptoms (p = 0.002, β = - 0.18). BPD symptoms significantly moderated the association between impaired mentalizing and depressive symptoms (p = 0.003), with more severe borderline symptoms associated with a stronger effect of poor mentalization on increased depressive symptoms.

conclusionMentalizing impairments occur in depression even after adjusting for the effect of BPD symptoms. Our findings help further characterise mentalizing impairments in depression, as well as the moderating effect of BPD symptoms on this association.. Further longitudinal work is required to investigate the direction of association.

Indexed as

BPDDepressionMentalization

Identifiers

PMID33947477
PMCPMC8097991
OpenAlexW3159748570

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.